HSPA1B

Gene Symbol	HSPA1B
Entrez Gene	3304
Alt Symbol	HSP70-1B, HSP70-2
Species	Human
Gene Type	protein-coding
Description	heat shock 70kDa protein 1B
Other Description	HSP70-1/HSP70-2|HSP70.1/HSP70.2|heat shock 70 kDa protein 1/2|heat shock 70 kDa protein 1A/1B|heat shock 70kD protein 1B
Swissprots	P19790 Q9UQL9 Q5SP17 Q9UQM0 Q5JQI4 P08107 B4E3B6
Accessions	AAA59845 AAA63227 AAD21815 BAB63299 EAX03529 AK295398 BAG58351 AK303967 BAG64891 AL360193 BC001876 BC057397 AAH57397 BC063507 AAH63507 DB015158 DQ896426 ABM87425 NM_005346 NP_005337
Function	In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation (PubMed:23973223). {ECO:0000269|PubMed:16537599, ECO:0000269|PubMed:23973223}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:17289661}. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Tissue Specificity	HSPA1B is testis-specific.
Top Pathways	Estrogen signaling pathway, Epstein-Barr virus infection, Legionellosis, Influenza A, Measles

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Anti-HSPA1B antibody - ab55288 from Abcam Prices $370.00 Sizes 100 µg Host Mouse Clonality Monoclonal

Anti-Heat Shock Protein 70 / HSPA1A Antibody - LS-C155344 from LifeSpan Bioscience Prices $335.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-HSP70 / Heat Shock Protein 70 Antibody (phospho-Tyr41) - LS-C313547 from LifeSpan Bioscience Prices $345.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Heat Shock Protein 70 / HSPA1A Antibody (aa492-541) IHC-plus™ - LS-B11555 from LifeSpan Bioscience Prices $450.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

HspA1B Antibody - NBP1-98547 from Novus Biologicals Prices $139.00, $329.00 Sizes 20 µl, 100 µl Host Rabbit Clonality Polyclonal

Hsp70 / Hsp72 Antibody - H00003303-B01P-50ug from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Monoclonal Anti-HSPA1B antibody produced in mouse - WH0003304M2 from Sigma-Aldrich Prices $347.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 3B7

HSPA1A Antibody (OAAB06758) - OAAB06758 from Aviva Systems Biology Prices $320.00 Sizes 400 µl Host Mouse Clonality Monoclonal Clone 201CT8.2.3

HSPA1A Antibody (OASA02855) - OASA02855 from Aviva Systems Biology Prices $430.00 Sizes 100 µg Host Mouse Clonality Monoclonal Clone 4E7

HSPA1B antibody - C-terminal region (ARP63869_P050) - ARP63869_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

HSPA1A Antibody (OAAB04607) - OAAB04607 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

HSPA1A Antibody (OAAB04609) - OAAB04609 from Aviva Systems Biology Prices $289.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

HSPA1B antibody - GTX106148 from GeneTex Prices $119.00 Sizes 25 μl Host Rabbit Clonality Polyclonal

HSPA1B antibody - GTX112963 from GeneTex Prices $119.00 Sizes 25 μl Host Rabbit Clonality Polyclonal

HSP70 antibody - 70R-12440 from Fitzgerald Prices $335.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti -HSP70 (C-terminus) (Heat Shock 70kD Protein 1A/1B, Heat Shock 70kD Protein 1/2,HSP70-1/HSP70-2, HSP70.1/HSP70.2, HSPA1A, HSPA1, HSX70, HSPA1B, HSP-70, HSP 70) - 223416 from USBiological Life Science Host Mouse Clonality Monoclonal Clone 15B185

Anti -HSP70 (Heat Shock 70kD Protein 1A/1B, Heat Shock 70kD Protein 1/2, HSP70-1/HSP70-2,HSP70.1/HSP70.2, HSPA1A, HSPA1, HSX70, HSPA1B, HSP-70, HSP 70) - 223417 from USBiological Life Science Host Rabbit Clonality Polyclonal

Anti -HSP70 (Heat Shock 70kD Protein 1A/1B, Heat Shock 70kD Protein 1/2, HSP70-1/HSP70-2,HSP70.1/HSP70.2, HSPA1A, HSPA1, HSX70, HSPA1B, HSP-70, HSP 70) - 223418 from USBiological Life Science Host Rabbit Clonality Polyclonal

Anti -HSP70 (N-terminus) (Heat Shock 70kD Protein 1A/1B, Heat Shock 70kD Protein 1/2,HSP70-1/HSP70-2, HSP70.1/HSP70.2, HSPA1A, HSPA1, HSX70, HSPA1B, HSP-70, HSP 70) - 223419 from USBiological Life Science Host Mouse Clonality Monoclonal Clone 15B186

Anti -HSP70, phosphorylated (Y41) (Heat Shock 70kD Protein 1A/1B, Heat Shock 70kD Protein1/2, HSP70-1/HSP70-2, HSP70.1/HSP70.2, HSPA1A, HSPA1, HSX70, HSPA1B, HSP-70, HSP 70) - 223420 from USBiological Life Science Host Rabbit Clonality Polyclonal

Mouse Anti-Human HSPA1A - 102-10102 from RayBiotech Host Mouse

Rabbit Anti-Human HSPA1A/HSPA1B (Y41) - 102-17425 from RayBiotech Host Rabbit

Rabbit Anti-Human HSPA1A/HSPA1B (Y525) - 102-17426 from RayBiotech Host Rabbit

Anti-Hsp70 Antibody - 10-P1813 from ARP American Research Products Prices $269.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

HSP70 antibody - 25405-1-AP from Proteintech Group Prices $279.00 Sizes con: 38 μg/150μl Host Rabbit Clonality Polyclonal

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