| Gene Symbol | Ndufs2 |
|---|---|
| Entrez Gene | 289218 |
| Alt Symbol | - |
| Species | Rat |
| Gene Type | protein-coding |
| Description | NADH dehydrogenase (ubiquinone) Fe-S protein 2 |
| Other Description | CI-49kD|NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial|NADH-ubiquinone oxidoreductase 49 kDa subunit|complex I-49kD|ndufs2 {ECO:0000312|EMBL:AAH82067.1} |
| Swissprots | Q641Y2 |
| Accessions | Q641Y2 BC082067 AAH82067 FQ215922 XM_003751277 XP_003751325 NM_001011907 NP_001011907 |
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250|UniProtKB:P17694}. |
| Subcellular Location | Mitochondrion inner membrane {ECO:0000269|PubMed:19343716}; Peripheral membrane protein {ECO:0000269|PubMed:19343716}; Matrix side {ECO:0000269|PubMed:19343716}. |
| Top Pathways | Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |