| Gene Symbol |
Ndufs2
|
| Entrez Gene |
289218
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
NADH dehydrogenase (ubiquinone) Fe-S protein 2
|
| Other Description |
CI-49kD|NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial|NADH-ubiquinone oxidoreductase 49 kDa subunit|complex I-49kD|ndufs2 {ECO:0000312|EMBL:AAH82067.1}
|
| Swissprots |
Q641Y2
|
| Accessions |
Q641Y2 BC082067 AAH82067 FQ215922 XM_003751277 XP_003751325 NM_001011907 NP_001011907
|
| Function |
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250|UniProtKB:P17694}.
|
| Subcellular Location |
Mitochondrion inner membrane {ECO:0000269|PubMed:19343716}; Peripheral membrane protein {ECO:0000269|PubMed:19343716}; Matrix side {ECO:0000269|PubMed:19343716}.
|
| Top Pathways |
Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation
|