| Gene Symbol | SELENBP1 |
|---|---|
| Entrez Gene | 8991 |
| Alt Symbol | HEL-S-134P, LPSB, SBP56, SP56, hSBP |
| Species | Human |
| Gene Type | protein-coding |
| Description | selenium binding protein 1 |
| Other Description | 56 kDa selenium-binding protein|epididymis secretory sperm binding protein Li 134P|selenium-binding protein 1 |
| Swissprots | B2RDR3 A6PVW9 B4E1F3 Q96GX7 Q49AQ8 B4DKP6 Q13228 A6NML9 |
| Accessions | EAW53443 EAW53444 EAW53445 Q13228 AK023875 BAB14709 AK296661 BAG59258 AK298355 BAG60599 AK303815 BAG64765 AK309264 AK310044 AK315643 BAG38010 BC009084 AAH09084 BC032997 AAH32997 BQ045424 CR456852 CAG33133 DB288439 DQ890731 ABM81657 EU794660 ACJ13714 HQ448237 ADQ32717 U29091 AAB02395 XM_011510110 XP_011508412 XM_011510111 XP_011508413 XR_921993 NM_001258288 NP_001245217 NM_001258289 NP_001245218 NM_003944 NP_003935 |
| Function | Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus. Cytoplasm, cytosol. Membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=May associate with Golgi membrane. May associate with the membrane of autophagosomes (By similarity). {ECO:0000250}. |
| Tissue Specificity | Highly expressed in liver, lung, colon, prostate, kidney and pancreas. In brain, present both in neurons and glia (at protein level). Down-regulated in lung adenocarcinoma, colorectal carcinoma and ovarian cancer. Two-fold up-regulated in brain and blood from schizophrenia patients. {ECO:0000269|PubMed:14991897, ECO:0000269|PubMed:16223876, ECO:0000269|PubMed:16380993, ECO:0000269|PubMed:16645984, ECO:0000269|PubMed:9679983}. |