Gene Symbol |
Pard6g
|
Entrez Gene |
93737
|
Alt Symbol |
2410049N21Rik, Par6a
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
par-6 family cell polarity regulator gamma
|
Other Description |
PAR-6 gamma|par-6 partitioning defective 6 homolog gamma|partitioning defective 6 homolog gamma|partitioning-defective protein 6, alpha
|
Swissprots |
Q9JK84
|
Accessions |
EDL09424 EDL09425 Q9JK84 AF252290 AAF71527 AK010699 AK019835 AK035811 BAC29195 AK163940 BB663070 BC025623 AAH25623 BC037678 AAH37678 BY732180 XM_006526527 XP_006526590 XR_386378 NM_053117 NP_444347
|
Function |
Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP- bound Rho small GTPases to atypical protein kinase C proteins (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasm. Cell membrane {ECO:0000250}. Cell junction, tight junction {ECO:0000250}.
|
Top Pathways |
Tight junction, Endocytosis, Hippo signaling pathway, Rap1 signaling pathway
|