Gene Symbol | Pard6g |
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Entrez Gene | 93737 |
Alt Symbol | 2410049N21Rik, Par6a |
Species | Mouse |
Gene Type | protein-coding |
Description | par-6 family cell polarity regulator gamma |
Other Description | PAR-6 gamma|par-6 partitioning defective 6 homolog gamma|partitioning defective 6 homolog gamma|partitioning-defective protein 6, alpha |
Swissprots | Q9JK84 |
Accessions | EDL09424 EDL09425 Q9JK84 AF252290 AAF71527 AK010699 AK019835 AK035811 BAC29195 AK163940 BB663070 BC025623 AAH25623 BC037678 AAH37678 BY732180 XM_006526527 XP_006526590 XR_386378 NM_053117 NP_444347 |
Function | Adapter protein involved in asymmetrical cell division and cell polarization processes. May play a role in the formation of epithelial tight junctions. The PARD6-PARD3 complex links GTP- bound Rho small GTPases to atypical protein kinase C proteins (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Cell membrane {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. |
Top Pathways | Tight junction, Endocytosis, Hippo signaling pathway, Rap1 signaling pathway |
PARD6G CRISPR/Cas9 KO Plasmid (m) - sc-430040 from Santa Cruz Biotechnology
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PARD6G HDR Plasmid (m) - sc-430040-HDR from Santa Cruz Biotechnology
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PARD6G Double Nickase Plasmid (m) - sc-430040-NIC from Santa Cruz Biotechnology
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PARD6G Double Nickase Plasmid (m2) - sc-430040-NIC-2 from Santa Cruz Biotechnology
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PARD6G CRISPR Activation Plasmid (m) - sc-430040-ACT from Santa Cruz Biotechnology
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PARD6G CRISPR Activation Plasmid (m2) - sc-430040-ACT-2 from Santa Cruz Biotechnology
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PARD6G Lentiviral Activation Particles (m) - sc-430040-LAC from Santa Cruz Biotechnology
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PARD6G Lentiviral Activation Particles (m2) - sc-430040-LAC-2 from Santa Cruz Biotechnology
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PARD6G siRNA (m) - sc-152025 from Santa Cruz Biotechnology
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PARD6G shRNA Plasmid (m) - sc-152025-SH from Santa Cruz Biotechnology
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PARD6G shRNA (m) Lentiviral Particles - sc-152025-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU029191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN38256 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND38256 from Sigma-Aldrich
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PARD6G siRNA (Mouse) - CRN0255 from Cohesion Biosciences
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shRNA set against Mouse PARD6G (NM_053117.3) - SHH370708 from Creative biogene
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Mouse PARD6G siRNA - orb289730 from Biorbyt
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PARD6G shRNA Plasmid (Mouse) - CHN0255 from Cohesion Biosciences
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