Gene Symbol | DENND5B |
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Entrez Gene | 160518 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | DENN/MADD domain containing 5B |
Other Description | DENN domain-containing protein 5B|rab6IP1-like protein |
Swissprots | Q6NUJ0 Q8WUC8 Q59FW8 Q68CZ7 Q8N973 Q6ZUT9 B5ME75 Q7Z3F9 |
Accessions | EAW88552 EAW88553 EAW88554 EAW88555 EAW88556 EAW88557 Q6ZUT9 AB209341 BAD92578 AF086301 AI762929 AI858532 AK021465 AK095598 BAC04583 AK123642 BAG53929 AK125323 BAC86129 AL137364 AL157581 BC020855 AAH20855 BC068580 AAH68580 BF513808 BM676905 BX537924 CAD97905 CR749639 CAH18433 XM_005253326 XP_005253383 XM_005253327 XP_005253384 XM_005253330 XP_005253387 XM_006719040 XP_006719103 XM_011520589 XP_011518891 XM_011520590 XP_011518892 XM_011520591 XP_011518893 NM_001308339 NP_001295268 NM_144973 NP_659410 |
Function | Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. {ECO:0000269|PubMed:20937701}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
DENND5B CRISPR/Cas9 KO Plasmid (h) - sc-414817 from Santa Cruz Biotechnology
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DENND5B HDR Plasmid (h) - sc-414817-HDR from Santa Cruz Biotechnology
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DENND5B Double Nickase Plasmid (h) - sc-414817-NIC from Santa Cruz Biotechnology
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DENND5B Double Nickase Plasmid (h2) - sc-414817-NIC-2 from Santa Cruz Biotechnology
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DENND5B CRISPR Activation Plasmid (h) - sc-414817-ACT from Santa Cruz Biotechnology
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DENND5B CRISPR Activation Plasmid (h2) - sc-414817-ACT-2 from Santa Cruz Biotechnology
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DENND5B Lentiviral Activation Particles (h) - sc-414817-LAC from Santa Cruz Biotechnology
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DENND5B Lentiviral Activation Particles (h2) - sc-414817-LAC-2 from Santa Cruz Biotechnology
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DENND5B siRNA (h) - sc-96051 from Santa Cruz Biotechnology
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DENND5B shRNA Plasmid (h) - sc-96051-SH from Santa Cruz Biotechnology
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DENND5B shRNA (h) Lentiviral Particles - sc-96051-V from Santa Cruz Biotechnology
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DENND5B RNAi - H00160518-R01 from Novus Biologicals
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MISSION® esiRNA - EHU060451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7146 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7146 from Sigma-Aldrich
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DENND5B siRNA (Human) - CRJ5906 from Cohesion Biosciences
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DENND5B - MBS8229732 from MyBioSource
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shRNA set against Human DENND5B (NM_144973.3) - SHH277117 from Creative biogene
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shRNA set against Human MGC24039(NM_144973.3) - SHH188129 from Creative biogene
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Human DENND5B siRNA - orb276407 from Biorbyt
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DENND5B shRNA Plasmid (Human) - CHJ5906 from Cohesion Biosciences
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DENND5B miRNA 3'UTR clone - MiUTR1H-06264 from Creative biogene
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