| Gene Symbol |
Jun
|
| Entrez Gene |
16476
|
| Alt Symbol |
AP-1, Junc, c-jun
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
jun proto-oncogene
|
| Other Description |
AH119|AP1|Jun oncogene|V-jun avian sarcoma virus 17 oncogene homolog|activator protein 1|immediate early|jun A|proto-oncogene c-jun|transcription factor AP-1
|
| Swissprots |
P05627
|
| Accessions |
CAP12263 P05627 AK132019 BAE20944 AK133722 AK133867 AK135023 BAE22389 AK140911 BAE24518 AK159196 BAE34891 AK159220 AY423853 AAR00344 BC002081 AAH02081 BC021888 AAH21888 BC032086 BC055887 BC094032 AAH94032 BY106462 J04115 AAA37419 X12740 CAA31236 X12761 CAA31252 NM_010591 NP_034721
|
| Function |
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. {ECO:0000269|PubMed:14707112, ECO:0000269|PubMed:17210646}.
|
| Subcellular Location |
Nucleus {ECO:0000250|UniProtKB:P05412}.
|
| Top Pathways |
Estrogen signaling pathway, TNF signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, Inflammatory bowel disease (IBD)
|