Gene Symbol | NOLC1 |
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Entrez Gene | 9221 |
Alt Symbol | NOPP130, NOPP140, NS5ATP13, P130 |
Species | Human |
Gene Type | protein-coding |
Description | nucleolar and coiled-body phosphoprotein 1 |
Other Description | 140 kDa nucleolar phosphoprotein|HCV NS5A trans-regulated protein 13|HCV NS5A-transactivated protein 13|hepatitis C virus NS5A-transactivated protein 13|nucleolar 130 kDa protein|nucleolar and coiled-body phosphprotein 1|nucleolar phosphoprotein p130|nucleolar protein p130 |
Swissprots | Q14978 Q9BUV3 Q15030 Q5VV70 |
Accessions | EAW49713 EAW49714 EAW49715 EAW49716 EAW49717 EAW49718 Q14978 AI937215 AK056755 BAG51805 AK225101 AK314363 BAG36995 AL520884 AY820769 AAV67777 BC001883 AAH01883 BC006769 AAH06769 BM473772 BM849059 CF145090 CN312242 D21262 BAA04803 DA588285 DQ891862 ABM82788 DQ895051 ABM85977 L37710 Z34289 CAA84063 XM_005270273 XP_005270330 NM_001284388 NP_001271317 NM_001284389 NP_001271318 NM_004741 NP_004732 |
Function | Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I. |
Subcellular Location | Nucleus, nucleolus. Cytoplasm. Note=Shuttles between the nucleolus and the cytoplasm. At telophase it begins to assemble into granular-like pre-nucleolar bodies which are subsequently relocated to nucleoli at the early G1-phase. |
Nopp140 CRISPR/Cas9 KO Plasmid (h) - sc-402907 from Santa Cruz Biotechnology
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Nopp140 HDR Plasmid (h) - sc-402907-HDR from Santa Cruz Biotechnology
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Nopp140 Double Nickase Plasmid (h) - sc-402907-NIC from Santa Cruz Biotechnology
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Nopp140 Double Nickase Plasmid (h2) - sc-402907-NIC-2 from Santa Cruz Biotechnology
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Nopp140 CRISPR Activation Plasmid (h) - sc-402907-ACT from Santa Cruz Biotechnology
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Nopp140 CRISPR Activation Plasmid (h2) - sc-402907-ACT-2 from Santa Cruz Biotechnology
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Nopp140 Lentiviral Activation Particles (h) - sc-402907-LAC from Santa Cruz Biotechnology
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Nopp140 Lentiviral Activation Particles (h2) - sc-402907-LAC-2 from Santa Cruz Biotechnology
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Nopp140 siRNA (h) - sc-38127 from Santa Cruz Biotechnology
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Nopp140 shRNA Plasmid (h) - sc-38127-SH from Santa Cruz Biotechnology
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Nopp140 shRNA (h) Lentiviral Particles - sc-38127-V from Santa Cruz Biotechnology
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NOLC1 RNAi - H00009221-R01 from Novus Biologicals
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MISSION® esiRNA - EHU082661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15405 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15405 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09898 from Sigma-Aldrich
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NOLC1 siRNA (Human) - CRH6105 from Cohesion Biosciences
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shRNA set against Human NOLC1(NM_004741.3) - SHR016122 from Creative biogene
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Human NOLC1 siRNA - orb266607 from Biorbyt
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NOLC1 shRNA Plasmid (Human) - CHH6105 from Cohesion Biosciences
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NOLC1 miRNA 3'UTR clone - MiUTR1H-06843 from Creative biogene
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