TPH1

Gene Symbol TPH1
Entrez Gene 7166
Alt Symbol TPRH, TRPH
Species Human
Gene Type protein-coding
Description tryptophan hydroxylase 1
Other Description L-tryptophan hydroxylase|indoleacetic acid-5-hydroxylase|tryptophan 5-hydroxylase 1|tryptophan 5-monooxygenase 1|tryptophan hydroxylase (tryptophan 5-monooxygenase)
Swissprots D3DQX6 O95189 Q3KPG8 O95188 Q16736 P17752
Accessions AAC69458 AAC69459 ACE96108 ACE96113 ACE96118 ACE96123 ACE96128 ACE96133 ACE96138 ACE96143 ACE96148 ACE96153 EAW68420 EAW68421 EAW68422 P17752 AY196344 AAO72075 AY196345 AAO72074 AY196346 AAO72076 BC106739 AAI06740 BC106740 AAI06741 BM451912 BP423529 X52836 CAA37018 NM_004179 NP_004170
Tissue Specificity Isoform 2 seems to be less widely expressed than isoform 1.
Top Pathways Tryptophan metabolism

TPH-1 (D10C10) Rabbit mAb - 12339 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D10C10
Western blot analysis of extracts from 293T cells, mock transfected (-) or transfected with a construct expressing full-length human TPH-1 (hTPH-1; +) and P815 cells, using TPH-1 (D10C10) Rabbit mAb (upper) or α/β-Tubulin Antibody #2148 (lower).

TPH (C-20) - sc-15116 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TPH (D-15) - sc-15114 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TPH (H-60) - sc-30079 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TPH (H-60): sc-30079. Western blot analysis of TPH expression in rat brain tissue extract.

p-TPH (Ser 58) - sc-135716 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
p-TPH (Ser 58): sc-135716. Western blot analysis of untreated (A) and cAMP-dependent protein kinase (PKA)-treated (B) rabbit recombinant TPH.

Anti-Tryptophan Hydroxylase (phospho S260) antibody - ab30574 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Tryptophan Hydroxylase (phospho S260) antibody (ab30574) at 1/1000 dilutionLane 1 : rat brain stem lysate (control)Lane 2 : rat brain stem lysate, incubated with S260 phosphopeptide (negative control)Lane 3 : rat brain stem lysate, incubated with corresponding non phosphopeptide.Lysates/proteins at 15 µg per lane.

Anti-Tryptophan Hydroxylase (phospho S260) antibody - ab138660 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Tryptophan Hydroxylase (phospho S260) antibody (ab138660) at 1/500 dilution + extracts from Jurkat cells and HepG2 cells at 30 µg

Anti-Tryptophan Hydroxylase (phospho S58) antibody - ab61068 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of paraffin-embedded human right temporal lobe using ab61068 at 1/50-1/100 dilution with or without immunising phosphopeptide.

Anti-Tryptophan Hydroxylase antibody - ab46757 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of Tryptophan Hydroxylase staining in Human normal colon formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab46757, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Tryptophan Hydroxylase antibody - ab111872 from Abcam

Prices $372.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Tryptophan Hydroxylase antibody - ab133209 from Abcam

Prices $384.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Tryptophan Hydroxylase antibody (ab133209) at 1/500 dilutionLane 1 : HepG2 cell lysateLane 2 : HepG2 cell lysate with Tryptophan Hydroxylase synthesized peptide

Anti-Tryptophan Hydroxylase antibody - ab61185 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Tryptophan Hydroxylase antibody (ab61185) at 1/500 dilutionLane 1 : HepG2 cell extractLane 2 : HepG2 cell extract with immunising peptide

Anti-Tryptophan Hydroxylase antibody - ab32821 from Abcam

Prices $376.00
Sizes 50 µl
Host Sheep
Clonality Polyclonal
Anti-Tryptophan Hydroxylase antibody (ab32821) at 1/1000 dilution + Human dorsal Raphe nucleus extract at 50 µgSecondaryAnti-Sheep HRP labelled.

Anti-Tryptophan Hydroxylase antibody [EP1311Y] - ab52954 from Abcam

Prices $391.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EP1311Y
Anti-Tryptophan Hydroxylase antibody [EP1311Y] (ab52954) at 1/500 dilution + THP-1 cell lysate at 10 µgSecondarygoat anti-rabbit HRP at 1/2000 dilution

Anti-Tryptophan Hydroxylase antibody [Try-63] - ab82244 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Try-63
IHC image of Tryptophan Hydroxylase staining in Human cerebral cortex formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab82244, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-Tryptophan Hydroxylase antibody [Try-63] - ab130212 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone Try-63
All lanes : Anti-Tryptophan Hydroxylase antibody [Try-63] (ab130212) at 0.5 µg/mlLane 1 : Rat brain tissue lysateLane 2 : Rat brain tissue lysate

Anti-TPH1 / Tryptophan Hydroxylase Antibody (phospho-Ser58) - LS-C43092 from LifeSpan Bioscience

Prices $585.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TPH1 / Tryptophan Hydroxylase Antibody - LS-C43104 from LifeSpan Bioscience

Prices $520.00
Sizes 100 µl
Host Sheep
Clonality Polyclonal

Anti-TPH1 / Tryptophan Hydroxylase Antibody (Val256) - LS-C177761 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of TPH1 (V256) pAb in paraffin-embedded human lung carcinoma tissue.

Anti-TPH1 / Tryptophan Hydroxylase Antibody - LS-C192921 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of THP-1 cell lines, using TPH1 antibody.

Anti-TPH1 / Tryptophan Hydroxylase Antibody (Lys54) - LS-C176562 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of TPH1 (K54) pAb in paraffin-embedded human brain tissue.

Anti-TPH1 / Tryptophan Hydroxylase Antibody (phospho-Ser260) - LS-C199690 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human lung carcinoma, using Tryptophan Hydroxylase (Phospho-Ser260) Antibody. The sample on the right was incubated with synthetic peptide.

Anti-TPH1 / Tryptophan Hydroxylase Antibody (phospho-Ser58) - LS-C199691 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human brain, using Tryptophan Hydroxylase (Phospho-Ser58) Antibody. The sample on the right was incubated with synthetic peptide.

Anti-TPH1 / TPH Antibody - LS-C331547 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of THP-1 cell lines, using TPH1 antibody.

Anti-TPH1 / Tryptophan Hydroxylase Antibody (aa35-62) - LS-C160136 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human brain tissue with TPH1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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