Gene Symbol | VCPKMT |
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Entrez Gene | 79609 |
Alt Symbol | C14orf138, METTL21D, VCP-KMT |
Species | Human |
Gene Type | protein-coding |
Description | valosin containing protein lysine (K) methyltransferase |
Other Description | VCP lysine methyltransferase|methyltransferase like 21D|methyltransferase-like protein 21D|protein-lysine methyltransferase METTL21D|valosin-containing protein lysine methyltransferase |
Swissprots | B7ZLA4 Q9H867 Q2M2X3 Q86T12 B7ZLA3 |
Accessions | CAE91187 Q9H867 AK023982 BAB14752 AK129564 BAC85183 BC027585 BC105118 AAI05119 BC143673 AAI43674 BC143674 AAI43675 BI753530 BI767189 BX247997 CAD62329 XM_005268060 XP_005268117 XM_006720254 XP_006720317 XM_011537154 XP_011535456 XR_429329 XR_943531 XR_943532 XR_943533 NM_001040662 NP_001035752 NM_024558 NP_078834 NR_049738 NR_049739 |
Function | Protein-lysine N-methyltransferase that specifically trimethylates 'Lys-315' of VCP/p97; this modification may decrease VCP ATPase activity. {ECO:0000269|PubMed:22948820, ECO:0000269|PubMed:23349634}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:23349634}. |
C14orf138 CRISPR/Cas9 KO Plasmid (h) - sc-413183 from Santa Cruz Biotechnology
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C14orf138 HDR Plasmid (h) - sc-413183-HDR from Santa Cruz Biotechnology
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C14orf138 Double Nickase Plasmid (h) - sc-413183-NIC from Santa Cruz Biotechnology
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C14orf138 Double Nickase Plasmid (h2) - sc-413183-NIC-2 from Santa Cruz Biotechnology
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C14orf138 CRISPR Activation Plasmid (h) - sc-413183-ACT from Santa Cruz Biotechnology
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C14orf138 CRISPR Activation Plasmid (h2) - sc-413183-ACT-2 from Santa Cruz Biotechnology
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C14orf138 Lentiviral Activation Particles (h) - sc-413183-LAC from Santa Cruz Biotechnology
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C14orf138 Lentiviral Activation Particles (h2) - sc-413183-LAC-2 from Santa Cruz Biotechnology
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C14orf138 siRNA (h) - sc-92351 from Santa Cruz Biotechnology
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C14orf138 shRNA Plasmid (h) - sc-92351-SH from Santa Cruz Biotechnology
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C14orf138 shRNA (h) Lentiviral Particles - sc-92351-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN1228 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1373 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1373 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1228 from Sigma-Aldrich
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VCPKMT siRNA (Human) - CRJ2424 from Cohesion Biosciences
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VCPKMT - MBS8229009 from MyBioSource
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shRNA set against Human METTL21D (NM_024558.2) - SHH340779 from Creative biogene
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shRNA set against Human C14orf138(NM_024558.2) - SHG114661 from Creative biogene
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shRNA set against Human C14orf138(NM_001040662.1) - SHG114895 from Creative biogene
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VCPKMT shRNA Plasmid (Human) - CHJ2424 from Cohesion Biosciences
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METTL21D miRNA 3'UTR clone - MiUTR1H-01096 from Creative biogene
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METTL21D miRNA 3'UTR clone - MiUTR1H-01097 from Creative biogene
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