Gene Symbol | SEMA4B |
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Entrez Gene | 10509 |
Alt Symbol | SEMAC, SemC |
Species | Human |
Gene Type | protein-coding |
Description | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B |
Other Description | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4B|semaphorin-4B |
Swissprots | Q9NPR2 Q6UXE3 Q8WVP9 Q96FK5 Q9C0B8 Q9H691 Q9NPM8 Q9NPN0 |
Accessions | EAX02084 EAX02085 EAX02086 Q9NPR2 AB051532 BAB21836 AF258561 AAG23764 AK026108 AK026133 BAB15372 AK027083 AK289991 BAF82680 AL390080 CAB98204 AL390081 CAB98205 AL390082 CAB98206 AY358392 AAQ88758 AY445887 AAR15707 BC010701 AAH10701 BC017658 AAH17658 BC019013 BC094849 AAH94849 BC110853 AAI10854 BC126438 AAI26439 BC144141 BX537671 CAD97806 CD109794 HQ258520 ADR83274 XM_011521160 XP_011519462 NM_020210 NP_064595 NM_198925 NP_945119 |
Function | Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Axon guidance |
SEMA4B CRISPR/Cas9 KO Plasmid (h) - sc-409785 from Santa Cruz Biotechnology
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SEMA4B HDR Plasmid (h) - sc-409785-HDR from Santa Cruz Biotechnology
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SEMA4B Double Nickase Plasmid (h) - sc-409785-NIC from Santa Cruz Biotechnology
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SEMA4B Double Nickase Plasmid (h2) - sc-409785-NIC-2 from Santa Cruz Biotechnology
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SEMA4B CRISPR Activation Plasmid (h) - sc-409785-ACT from Santa Cruz Biotechnology
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SEMA4B CRISPR Activation Plasmid (h2) - sc-409785-ACT-2 from Santa Cruz Biotechnology
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SEMA4B Lentiviral Activation Particles (h) - sc-409785-LAC from Santa Cruz Biotechnology
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SEMA4B Lentiviral Activation Particles (h2) - sc-409785-LAC-2 from Santa Cruz Biotechnology
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SEMA4B siRNA (h) - sc-90197 from Santa Cruz Biotechnology
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SEMA4B shRNA Plasmid (h) - sc-90197-SH from Santa Cruz Biotechnology
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SEMA4B shRNA (h) Lentiviral Particles - sc-90197-V from Santa Cruz Biotechnology
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Semaphorin 4B RNAi - H00010509-R03 from Novus Biologicals
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MISSION® esiRNA - EHU137751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19071 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19071 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07842 from Sigma-Aldrich
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Semaphorin 4B RNAi - H00010509-R04 from Novus Biologicals
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shRNA set against Human SEMA4B (NM_020210.3) - SHH404280 from Creative biogene
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SEMA4B miRNA 3'UTR clone - MiUTR1H-09253 from Creative biogene
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SEMA4B miRNA 3'UTR clone - MiUTR3H-16039 from Creative biogene
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