ACOT7

Gene Symbol	ACOT7
Entrez Gene	11332
Alt Symbol	ACH1, ACT, BACH, CTE-II, LACH, LACH1, hBACH
Species	Human
Gene Type	protein-coding
Description	acyl-CoA thioesterase 7
Other Description	CTE-IIa|acyl-CoA thioesterase 2|acyl-CoA thioesterase, long chain|brain acyl CoA hydrolase|brain acyl-CoA hydrolase|cytosolic acyl coenzyme A thioester hydrolase|long chain acyl-CoA thioester hydrolase
Swissprots	B3KQ12 A8K0K7 A8K232 Q9Y539 Q53Y78 Q5JYL5 O43703 Q9UJM9 A8K6B8 A8K837 Q5JYL4 Q5JYL6 Q5JYL2 Q9Y540 Q5JYL3 O00154 Q5TGR4
Accessions	EAW71527 EAW71528 EAW71529 EAW71530 EAW71531 EAW71532 O00154 AB074415 BAC20174 AB074416 BAC20175 AB074417 BAC20176 AB074418 BAC20177 AB074419 BAC20178 AK057168 BAG51874 AK289572 BAF82261 AK290097 BAF82786 AK291583 BAF84272 AK292202 BAF84891 AK300831 BAG62482 AK304465 BAH14193 AL702662 BC017365 AAH17365 BG332214 BM807217 BQ067921 BT006888 AAP35534 BU594651 D88894 BAA24350 U91316 AAB61211 NM_007274 NP_009205 NM_181864 NP_863654 NM_181865 NP_863655 NM_181866 NP_863656 NM_181862 NM_181863
Function	Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May play an important physiological function in brain. May play a regulatory role by modulating the cellular levels of fatty acyl- CoA ligands for certain transcription factors as well as the substrates for fatty acid metabolizing enzymes, contributing to lipid homeostasis. Has broad specificity, active towards fatty acyl-CoAs with chain-lengths of C8-C18. Has a maximal activity toward palmitoyl-CoA.
Subcellular Location	Isoform 1: Mitochondrion.
Tissue Specificity	Isoform 4 is expressed exclusively in brain. {ECO:0000269|PubMed:12435388}.
Top Pathways	Fatty acid elongation, Biosynthesis of unsaturated fatty acids

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ACOT7 293T Cell Transient Overexpression Lysate(Denatured) - H00011332-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

ACOT7 overexpression lysate - LY405559 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

ACOT7 overexpression lysate - LY405560 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

ACOT7 overexpression lysate - LY405561 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

ACOT7 293 Cell Lysate - 403650 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

ACOT7 Over-expression Lysate Product - GWB-EB7170 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

ACOT7 Overexpression Lysate (Native) - NBP2-04869 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

ACOT7 Overexpression Lysate (Denatured) - H00011332-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Panoply™ Human ACOT7 Knockdown Stable Cell Line - CSC-DC000147 from Creative biogene Category Cell Line Species Human

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