Gene Symbol | NTN4 |
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Entrez Gene | 59277 |
Alt Symbol | PRO3091 |
Species | Human |
Gene Type | protein-coding |
Description | netrin 4 |
Other Description | beta-netrin|hepar-derived netrin-like protein|netrin-4 |
Swissprots | Q9NT44 Q7Z5B6 Q9HB63 B2RNC2 Q9P133 Q7L9D6 Q9BZP1 Q658K9 Q7L3F1 |
Accessions | CCQ43667 EAW97544 EAW97545 Q9HB63 AF119916 AAF69670 AF278532 AAG30822 AF297711 AAG53651 AK024691 BAB14964 AK026833 AK226070 AK290591 BAF83280 AK315796 BAG38140 AL137540 CAB70800 AL833767 CAH56243 AY330211 AAP92113 BC013591 AAH13591 BC136798 AAI36799 BC136799 AAI36800 BI549738 Z50158 XM_011538629 XP_011536931 NM_021229 NP_067052 |
Function | May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants. {ECO:0000269|PubMed:11038171}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000269|PubMed:11038171}. Note=Major component. |
Tissue Specificity | Expressed in kidney, spleen, mammary gland, aorta, heart, ovary, prostate and fetal spleen. {ECO:0000269|PubMed:11038171}. |
Top Pathways | Axon guidance |
netrin-4 CRISPR/Cas9 KO Plasmid (h) - sc-403229 from Santa Cruz Biotechnology
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netrin-4 HDR Plasmid (h) - sc-403229-HDR from Santa Cruz Biotechnology
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netrin-4 Double Nickase Plasmid (h) - sc-403229-NIC from Santa Cruz Biotechnology
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netrin-4 Double Nickase Plasmid (h2) - sc-403229-NIC-2 from Santa Cruz Biotechnology
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netrin-4 CRISPR Activation Plasmid (h) - sc-403229-ACT from Santa Cruz Biotechnology
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netrin-4 CRISPR Activation Plasmid (h2) - sc-403229-ACT-2 from Santa Cruz Biotechnology
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netrin-4 Lentiviral Activation Particles (h) - sc-403229-LAC from Santa Cruz Biotechnology
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netrin-4 Lentiviral Activation Particles (h2) - sc-403229-LAC-2 from Santa Cruz Biotechnology
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netrin-4 siRNA (h) - sc-44504 from Santa Cruz Biotechnology
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netrin-4 shRNA Plasmid (h) - sc-44504-SH from Santa Cruz Biotechnology
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netrin-4 shRNA (h) Lentiviral Particles - sc-44504-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU084771 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15564 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15564 from Sigma-Aldrich
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NTN4 siRNA (Human) - CRJ1763 from Cohesion Biosciences
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netrin-4 CRISPR/Cas9 KO Plasmid (h2) - sc-403229-KO-2 from Santa Cruz Biotechnology
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netrin-4 HDR Plasmid (h2) - sc-403229-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human NTN4 (NM_021229.3) - SHH355724 from Creative biogene
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NTN4 shRNA Plasmid (Human) - CHJ1763 from Cohesion Biosciences
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NTN4 miRNA 3'UTR clone - MiUTR1H-06945 from Creative biogene
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