Gene Symbol | ALDH6A1 |
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Entrez Gene | 4329 |
Alt Symbol | MMSADHA, MMSDH |
Species | Human |
Gene Type | protein-coding |
Description | aldehyde dehydrogenase 6 family, member A1 |
Other Description | malonate-semialdehyde dehydrogenase|methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial|mitochondrial acylating methylmalonate-semialdehyde dehydrogenase |
Swissprots | J3KNU8 B4DFS8 B2R609 Q02252 Q9UKM8 |
Accessions | AAG29581 EAW81158 EAW81159 EAW81160 Q02252 AF038011 AAB92620 AF148505 AAF04489 AF159889 AAF80380 AI244036 AJ249994 CAB76468 AK222687 BAD96407 AK223244 BAD96964 AK294243 BAG57539 AK311478 AK312389 BAG35306 AW418653 BC004909 AAH04909 BC032371 AAH32371 DQ892921 ABM83847 DQ893680 ABM84606 EU176729 ABW03530 M93405 AAA36328 NM_001278593 NP_001265522 NM_001278594 NP_001265523 NM_005589 NP_005580 |
Function | Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA. |
Subcellular Location | Mitochondrion. |
Top Pathways | Inositol phosphate metabolism, Carbon metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism |
ALDH6A1 CRISPR/Cas9 KO Plasmid (h) - sc-406553 from Santa Cruz Biotechnology
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ALDH6A1 HDR Plasmid (h) - sc-406553-HDR from Santa Cruz Biotechnology
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ALDH6A1 Double Nickase Plasmid (h) - sc-406553-NIC from Santa Cruz Biotechnology
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ALDH6A1 Double Nickase Plasmid (h2) - sc-406553-NIC-2 from Santa Cruz Biotechnology
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ALDH6A1 CRISPR Activation Plasmid (h) - sc-406553-ACT from Santa Cruz Biotechnology
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ALDH6A1 CRISPR Activation Plasmid (h2) - sc-406553-ACT-2 from Santa Cruz Biotechnology
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ALDH6A1 Lentiviral Activation Particles (h) - sc-406553-LAC from Santa Cruz Biotechnology
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ALDH6A1 Lentiviral Activation Particles (h2) - sc-406553-LAC-2 from Santa Cruz Biotechnology
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ALDH6A1 siRNA (h) - sc-92361 from Santa Cruz Biotechnology
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ALDH6A1 shRNA Plasmid (h) - sc-92361-SH from Santa Cruz Biotechnology
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ALDH6A1 shRNA (h) Lentiviral Particles - sc-92361-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU015761 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2300 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2300 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05093 from Sigma-Aldrich
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ALDH6A1 siRNA (Human) - CRH2940 from Cohesion Biosciences
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ALDH6A1 - MBS8221021 from MyBioSource
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ALDH6A1 CRISPR/Cas9 KO Plasmid (h2) - sc-406553-KO-2 from Santa Cruz Biotechnology
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ALDH6A1 HDR Plasmid (h2) - sc-406553-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human ALDH6A1 (NM_005589.2) - SHH234950 from Creative biogene
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shRNA set against Human ALDH6A1(NM_005589.2) - SHG052825 from Creative biogene
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ALDH6A1 shRNA Plasmid (Human) - CHH2940 from Cohesion Biosciences
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ALDH6A1 miRNA 3'UTR clone - MiUTR1H-00294 from Creative biogene
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