Gene Symbol | FCGR2A |
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Entrez Gene | 2212 |
Alt Symbol | CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, FcGR, IGFR2 |
Species | Human |
Gene Type | protein-coding |
Description | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
Other Description | Immunoglobulin G Fc receptor II|fc-gamma RII-a|fc-gamma-RIIa|fcRII-a|igG Fc receptor II-a|low affinity immunoglobulin gamma Fc region receptor II-a |
Swissprots | Q8WW64 P12318 Q8WUN1 |
Accessions | AAL99539 ABK41920 CAA01563 CAA48217 P12318 AF416711 AAL78867 AI250177 AK225438 AK225601 AK226059 AK298657 BAH12840 AK298734 BAH12860 AK315225 BAG37654 BC019931 AAH19931 BC020823 AAH20823 DQ892037 ABM82963 DQ895228 ABM86154 J03619 AAA35932 M28697 AAA36050 M31932 AAA35827 X62572 Y00644 CAA68672 XM_011509287 XP_011507589 XM_011509288 XP_011507590 XM_011509289 XP_011507591 XM_011509290 XP_011507592 XM_011509291 XP_011507593 NM_001136219 NP_001129691 NM_021642 NP_067674 |
Function | Binds to the Fc region of immunoglobulins gamma. Low affinity receptor. By binding to IgG it initiates cellular responses against pathogens and soluble antigens. Promotes phagocytosis of opsonized antigens. {ECO:0000269|PubMed:19011614}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:19011614}; Single-pass type I membrane protein {ECO:0000269|PubMed:19011614}. |
Tissue Specificity | Found on monocytes, neutrophils and eosinophil platelets. |
Top Pathways | Systemic lupus erythematosus, Fc gamma R-mediated phagocytosis, Leishmaniasis, Phagosome, Staphylococcus aureus infection |
FCGR2A-Over-expression-Lysate - LY11154a from Abgent, a WuXi AppTec company
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FCGR2A overexpression lysate - LY402871 from Acris Antibodies
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FCGR2A 293 Cell Lysate - 402497 from ABBIOTEC
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Fc gamma RIIA/CD32a Overexpression Lysate (Native) - NBL1-10655 from Novus Biologicals
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CD32-A (h2): 293T Lysate - sc-174810 from Santa Cruz Biotechnology
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FCGR2A Over-expression Lysate Product - GWB-561D05 from Genway Biotech
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Rhesus CD32a / FCGR2A HEK293 Cell Lysate (WB positive control) - 90016-C08HL-300 from Sino Biological
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Cynomolgus CD32a / FCGR2A HEK293 Cell Lysate (WB positive control) - 90015-C27HL-300 from Sino Biological
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Cynomolgus CD32a / FCGR2A HEK293 Cell Lysate (WB positive control) - 90015-C08HL-300 from Sino Biological
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Human CD32a / FCGR2A HEK293 Cell Lysate (WB positive control) - 10374-H27HL-300 from Sino Biological
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Human CD32a / FCGR2A HEK293 Cell Lysate (WB positive control) - 10374-H27H1L-300 from Sino Biological
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Human CD32a / FCGR2A HEK293 Cell Lysate (WB positive control) - 10374-H08HL-300 from Sino Biological
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Human CD32a / FCGR2A HEK293 Cell Lysate (WB positive control) - 10374-H08H1L-300 from Sino Biological
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Human CD32a / FCGR2A CHO Cell Lysate (WB positive control) - 10374-H08CL-300 from Sino Biological
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Human CD32a / FCGR2A (167 His) CHO Cell Lysate (WB positive control) - 10374-H08C1L-300 from Sino Biological
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Human CD32a / FCGR2A Insect Cell Lysate (WB positive control) - 10374-H08BL-300 from Sino Biological
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Human CD32a / FCGR2A HEK293 Cell Lysate (WB positive control) - 10374-H02HL-300 from Sino Biological
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Human CD32a Human Cells Transfected Lysate (positive control) (denatured) - orb173748 from Biorbyt
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Human CD32a Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb174954 from Biorbyt
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Fc gamma RIIA/CD32a Overexpression Lysate (Denatured) - H00002212-T01 from Novus Biologicals
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Human CD32a Human Cells Transfected Lysate (positive control) (denatured) - orb173513 from Biorbyt
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Human CD32a (167 His) CHO Transfected Lysate (positive control) (denatured) - orb175604 from Biorbyt
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Human CD32a Human Cells Transfected Lysate (positive control) (denatured) - orb172863 from Biorbyt
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Human CD32a CHO Transfected Lysate (positive control) (denatured) - orb175349 from Biorbyt
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Human CD32a Human Cells Transfected Lysate (positive control) (denatured) - orb173749 from Biorbyt
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