| Gene Symbol |
ROBO2
|
| Entrez Gene |
6092
|
| Alt Symbol |
SAX3
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
roundabout, axon guidance receptor, homolog 2 (Drosophila)
|
| Other Description |
roundabout homolog 2
|
| Swissprots |
Q19AB5 Q9HCK4 O43608 Q19AB4
|
| Accessions |
AFG72969 AFG72970 AFG72971 EAW68889 Q9HCK4 AB046788 BAB13394 AF040991 AAC39576 AK074780 BAC11205 AK301176 BAG62763 BC064374 AAH64374 BC144302 BC144303 BC144306 BC146772 AAI46773 BX648828 DQ533873 ABF83430 DQ533874 ABF83431 XM_011533981 XP_011532283 XM_011533982 XP_011532284 XM_011533983 XP_011532285 XM_011533984 XP_011532286 XM_011533985 XP_011532287 NM_001128929 NP_001122401 NM_001290039 NP_001276968 NM_001290040 NP_001276969 NM_001290065 NP_001276994 NM_002942 NP_002933
|
| Function |
Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
|
| Top Pathways |
Axon guidance
|
