GRIN2C

Gene Symbol GRIN2C
Entrez Gene 2905
Alt Symbol GluN2C, NMDAR2C, NR2C
Species Human
Gene Type protein-coding
Description glutamate receptor, ionotropic, N-methyl D-aspartate 2C
Other Description N-methyl D-aspartate receptor subtype 2C|N-methyl-D-aspartate receptor subunit 2C|glutamate [NMDA] receptor subunit epsilon-3|glutamate receptor ionotropic, NMDA 2C
Swissprots B2RTT1 Q14957
Accessions EAW89202 EAW89203 EAW89204 Q14957 AB208799 BAD92036 BC031077 AAH31077 BC041128 AAH41128 BC059384 AAH59384 BC140801 AAI40802 BC144586 BM686026 L76224 AAA88096 U77782 AAB71624 XM_006721845 XP_006721908 XM_006721846 XP_006721909 XM_011524686 XP_011522988 XM_011524687 XP_011522989 XM_011524688 XP_011522990 XM_011524689 XP_011522991 XM_011524690 XP_011522992 XM_011524691 XP_011522993 XM_011524692 XP_011522994 NM_000835 NP_000826 NM_001278553 NP_001265482 NR_103735
Function NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
Subcellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Tissue Specificity Mainly expressed in brain with predominant expression is in the cerebellum, also present in the hippocampus, amygdala, caudate nucleus, corpus callosum, subthalamic nuclei and thalamus. Detected in the heart, skeletal muscle and pancreas.
Top Pathways Amphetamine addiction, cAMP signaling pathway, Circadian entrainment, Alcoholism, Cocaine addiction

NMDAε3 (C-20) - sc-1470 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NMDAε3 (C-20): sc-1470. Western blot analysis of NMDAε3 expression in mouse cerebellum tissue extract.

NMDAε3 (D-20) - sc-31547 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

NMDAε3 (H-16) - sc-31550 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NMDAε3 (H-16): sc-31550. Western blot analysis of NMDAε3 expression in mouse cerebellum tissue extract.

NMDAε3 (H-80) - sc-50437 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NMDAε3 (H-80): sc-50437. Immunoperoxidase staining of formalin fixed, paraffin-embedded human bronchus tissue showing cytoplasmic staining of respiratory epithelial cells.

NMDAε3 (K-17) - sc-31549 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NMDAε3 (K-17): sc-31549. Immunoperoxidase staining of formalin fixed, paraffin-embedded human heart muscle tissue showing cytoplasmic staining of myocytes.

Anti-NMDAR2C antibody - ab105146 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-NMDAR2C antibody - ab191524 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NMDAR2C antibody (ab191524)Lane 1 : SKOVCAR whole cell lysateLane 2 : HEK293T whole cell lysateLane 3 : sp2/0 whole cell lysate

Anti-NMDAR2C antibody - ab110 from Abcam

Prices $370.00
Sizes 10 µg
Host Rabbit
Clonality Polyclonal

Anti-GRIN2C / NMDAR2C / NR2C Antibody (aa567-595, APC) - LS-C214960 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIN2C / NMDAR2C / NR2C Antibody (aa567-595, Biotin) - LS-C214961 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIN2C / NMDAR2C / NR2C Antibody (aa567-595, FITC) - LS-C214962 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIN2C / NMDAR2C / NR2C Antibody (aa25-130) - LS-C49203 from LifeSpan Bioscience

Prices $365.00
Sizes 10 µg
Host Rabbit
Clonality Polyclonal
This antibody recognizes the 180 kDa 2A and 2B subunits, however, this blot was done done on the cerebellum of an older animal where there is not much 2A and 2B present. In a younger animal, you will see the 180 kDa band clearly.

Anti-GRIN2C / NMDAR2C / NR2C Antibody (aa567-595, Azide-free, HRP) - LS-C214963 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIN2C / NMDAR2C / NR2C Antibody - LS-C308121 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GRIN2C / NMDAR2C / NR2C Antibody (aa567-595, PE) - LS-C214965 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIN2C / NMDAR2C / NR2C Antibody (C-Terminus) - LS-C152952 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
WB: Rat Brain lysate was resolved by electrophoresis, transferred to PVDF and probed with anti-NMDAR2C, clone G218B5 (1:1000 dilution). Proteins were visualized using Goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Arrow indicates NMDAR2C (~135 kDa).

Anti-GRIN2C / NMDAR2C / NR2C Antibody - LS-C310521 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIN2C / NMDAR2C / NR2C Antibody - LS-C310522 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GRIN2C / NMDAR2C / NR2C Antibody (aa567-595) - LS-C329605 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIN2C / NMDAR2C / NR2C Antibody (phospho-Ser1096) - LS-C150367 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GRIN2C / NMDAR2C / NR2C Antibody - LS-C340981 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GRIN2C / NMDAR2C / NR2C Antibody (Pro986) - LS-C177600 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of NMDA3 (P986) pAb in paraffin-embedded human brain tissue.

Anti-GRIN2C / NMDAR2C / NR2C Antibody (aa567-595) - LS-C157785 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GRIN2C Antibody western blot of mouse cerebellum tissue lysates (35 ug/lane). The GRIN2C antibody detected the GRIN2C protein (arrow).

Anti-GRIN2C / NMDAR2C / NR2C Antibody (N-Terminus) - LS-C202 from LifeSpan Bioscience

Prices $355.00
Sizes 10 µg
Host Rabbit
Clonality Polyclonal
Western blot of 10 ug of rat cerebellar lysate showing specific immunolabeling of the ~140k NR2C subunit of the NMDA receptor.

Anti-GRIN2C / NMDAR2C / NR2C Antibody (aa69-118) IHC-plus™ - LS-B962 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GRIN2C / NMDAR2C antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B962 concentration 5 ug/ml.
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