| Gene Symbol |
ZBTB32
|
| Entrez Gene |
27033
|
| Alt Symbol |
FAXF, FAZF, Rog, TZFP, ZNF538
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zinc finger and BTB domain containing 32
|
| Other Description |
FANCC-interacting protein|fanconi anemia zinc finger protein|repressor of GATA|testis zinc finger protein|zinc finger and BTB domain-containing protein 32|zinc finger protein 538
|
| Swissprots |
Q9Y2Y4 Q8WVP2
|
| Accessions |
Q9Y2Y4 AF130255 AAD27708 AF165097 AAD48448 BC017700 AAH17700 XM_005258739 XP_005258796 XM_011526718 XP_011525020 XM_011526719 XP_011525021 XM_011526720 XP_011525022 XR_935792 XR_935793 NM_014383 NP_055198
|
| Function |
DNA-binding protein that binds to the to a 5'- TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:10572087}. Note=Located in nuclear speckles.
|
| Tissue Specificity |
Predominantly expressed in testis. Some isoforms are ubiquitously expressed. {ECO:0000269|PubMed:10544010}.
|