Gene Symbol | EARS2 |
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Entrez Gene | 124454 |
Alt Symbol | COXPD12, MSE1 |
Species | Human |
Gene Type | protein-coding |
Description | glutamyl-tRNA synthetase 2, mitochondrial |
Other Description | gluRS|glutamate tRNA ligase 2, mitochondrial|glutamate--tRNA ligase|probable glutamate--tRNA ligase, mitochondrial|probable glutamyl-tRNA synthetase, mitochondrial |
Swissprots | B3KTT2 D3DWF1 Q8TF31 Q86YH3 Q5JPH6 |
Accessions | AAC05815 EAW55821 EAW55822 EAW55823 EAW55824 EAW55825 Q5JPH6 AB075850 BAB85556 AF088053 AK095998 BAG53194 AL832489 CAI46121 BC020592 BC040013 AAH40013 BX648129 CA306283 DA692403 EU832445 ACE87617 EU832528 ACE86930 JF432834 ADZ16051 XM_006721020 XP_006721083 XM_011545738 XP_011544040 XM_011545739 XP_011544041 NM_001083614 NP_001077083 NM_001308211 NP_001295140 NR_003501 |
Function | Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). {ECO:0000250}. |
Subcellular Location | Mitochondrion matrix {ECO:0000250}. |
Top Pathways | Porphyrin and chlorophyll metabolism, Aminoacyl-tRNA biosynthesis |
GluRS CRISPR/Cas9 KO Plasmid (h) - sc-406549 from Santa Cruz Biotechnology
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GluRS HDR Plasmid (h) - sc-406549-HDR from Santa Cruz Biotechnology
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GluRS Double Nickase Plasmid (h) - sc-406549-NIC from Santa Cruz Biotechnology
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GluRS Double Nickase Plasmid (h2) - sc-406549-NIC-2 from Santa Cruz Biotechnology
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GluRS CRISPR Activation Plasmid (h) - sc-406549-ACT from Santa Cruz Biotechnology
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GluRS CRISPR Activation Plasmid (h2) - sc-406549-ACT-2 from Santa Cruz Biotechnology
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GluRS Lentiviral Activation Particles (h) - sc-406549-LAC from Santa Cruz Biotechnology
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GluRS Lentiviral Activation Particles (h2) - sc-406549-LAC-2 from Santa Cruz Biotechnology
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GluRS siRNA (h) - sc-75146 from Santa Cruz Biotechnology
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GluRS shRNA Plasmid (h) - sc-75146-SH from Santa Cruz Biotechnology
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GluRS shRNA (h) Lentiviral Particles - sc-75146-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU022101 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7615 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7615 from Sigma-Aldrich
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EARS2 siRNA (Human) - CRJ4764 from Cohesion Biosciences
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EARS2 - MBS8205156 from MyBioSource
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shRNA set against Human EARS2(NM_001083614.1) - SHH022607 from Creative biogene
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EARS2 shRNA Plasmid (Human) - CHJ4764 from Cohesion Biosciences
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EARS2 miRNA 3'UTR clone - MiUTR1H-03084 from Creative biogene
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