| Gene Symbol |
Ap1s1
|
| Entrez Gene |
11769
|
| Alt Symbol |
AP19
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
adaptor protein complex AP-1, sigma 1
|
| Other Description |
AP-1 complex subunit sigma-1A|HA1 19 kDa subunit|adapter-related protein complex 1 sigma-1A subunit|adapter-related protein complex 1 subunit sigma-1A|adaptor protein complex AP-1 sigma-1A subunit|adaptor protein complex AP-1 subunit sigma-1A|adaptor-related protein complex 1 subunit sigma-1A|adaptor-related protein complex AP-1, sigma 1|clathrin assembly protein complex 1 sigma-1A small chain|clathrin coat assembly protein AP19|golgi adaptor HA1/AP1 adaptin sigma-1A subunit|sigma 1a subunit of AP-1 clathrin|sigma-adaptin 1A|sigma1A-adaptin
|
| Swissprots |
P61967
|
| Accessions |
EDL19288 EDL19289 P61967 AK002225 BAB21947 AK183413 AK192071 AK196123 AK213207 BC052692 AAH52692 M62418 AAA37243 XM_006504347 XP_006504410 XM_006504348 XP_006504411 NM_007457 NP_031483
|
| Function |
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
|
| Subcellular Location |
Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
|
| Tissue Specificity |
Detected in brain and embryonic stem cells.
|
| Top Pathways |
Lysosome
|