| Gene Symbol |
TMED3
|
| Entrez Gene |
23423
|
| Alt Symbol |
C15orf22, P24B, p26
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane emp24 protein transport domain containing 3
|
| Other Description |
integral type I protein|membrane protein p24B|p24 family protein gamma-4|p24gamma4|transmembrane emp24 domain-containing protein 3
|
| Swissprots |
Q2T9F8 Q9Y3Q3 B4DN05 A8K069
|
| Accessions |
EAW99138 EAW99139 Q9Y3Q3 AI243096 AJ132270 CAB40416 AK075529 BAC11674 AK222516 BAD96236 AK289434 BAF82123 AK297710 BAG60067 AK304148 BAG65039 AL109672 CAB52017 AL109673 CAB52018 AY358974 AAQ89333 BC000027 AAH00027 BC010853 AAH10853 BC017495 AAH17495 BC022232 AAH22232 BC111547 AAI11548 BM549126 BM699123 BP260160 CR457384 CAG33665 NM_001301203 NP_001288132 NM_007364 NP_031390 NR_125394
|
| Function |
Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. {ECO:0000269|PubMed:10852829}.
|
| Subcellular Location |
Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Golgi apparatus, Golgi stack membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, COPI-coated vesicle membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=Probably cycles between compartments of the early secretatory pathway.
|
![Western Blot: TMED3 Overexpression Lysate (Adult Normal) [NBL1-16982] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TMED3.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9170_TMED3%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16982-img0002.jpg)