SDHC
| Gene Symbol | SDHC |
|---|---|
| Entrez Gene | 6391 |
| Alt Symbol | CYB560, CYBL, PGL3, QPS1, SDH3 |
| Species | Human |
| Gene Type | protein-coding |
| Description | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa |
| Other Description | cytochrome B large subunit of complex II|integral membrane protein CII-3b|succinate dehydrgenase cytochrome b|succinate dehydrogenase 3, integral membrane subunit|succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD|succinate dehydrogenase cytochrome b560 subunit, mitochondrial|succinate-ubiquinone oxidoreductase cytochrome B large subunit |
| Swissprots | Q5VTH3 Q99643 Q3C259 O75609 Q3C2H4 Q3C2D8 |
| Accessions | AAC27993 EAW52597 EAW52598 EAW52599 EAW52600 EAW52601 EAW52602 EAW52603 EAW52604 Q99643 AB201252 BAE46977 AB211234 BAE46978 AB211235 BAE46979 AB212048 BAE46980 AK131051 AK293687 BAG57126 AK294305 BAG57586 BC012735 BC020808 AAH20808 BC033626 AAH33626 BC066329 AAH66329 BG724095 CR457102 CAG33383 D49737 BAA31998 DA751501 U57877 AAB41838 NM_001035511 NP_001030588 NM_001035512 NP_001030589 NM_001035513 NP_001030590 NM_001278172 NP_001265101 NM_003001 NP_002992 NR_103459 |
| Function | Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). |
| Subcellular Location | Mitochondrion inner membrane; Multi-pass membrane protein. |
| Top Pathways | Citrate cycle (TCA cycle), Alzheimer's disease, Huntington's disease, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation |
SDHC CRISPR/Cas9 KO Plasmid (h) - sc-405559 from Santa Cruz Biotechnology
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SDHC HDR Plasmid (h) - sc-405559-HDR from Santa Cruz Biotechnology
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SDHC Double Nickase Plasmid (h) - sc-405559-NIC from Santa Cruz Biotechnology
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SDHC Double Nickase Plasmid (h2) - sc-405559-NIC-2 from Santa Cruz Biotechnology
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SDHC CRISPR Activation Plasmid (h) - sc-405559-ACT from Santa Cruz Biotechnology
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SDHC CRISPR Activation Plasmid (h2) - sc-405559-ACT-2 from Santa Cruz Biotechnology
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SDHC Lentiviral Activation Particles (h) - sc-405559-LAC from Santa Cruz Biotechnology
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SDHC Lentiviral Activation Particles (h2) - sc-405559-LAC-2 from Santa Cruz Biotechnology
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SDHC siRNA (h) - sc-61510 from Santa Cruz Biotechnology
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SDHC shRNA Plasmid (h) - sc-61510-SH from Santa Cruz Biotechnology
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SDHC shRNA (h) Lentiviral Particles - sc-61510-V from Santa Cruz Biotechnology
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SDHC RNAi - H00006391-R02 from Novus Biologicals
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SDHC RNAi - H00006391-R01 from Novus Biologicals
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SDHC RNAi - H00006391-R03 from Novus Biologicals
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MISSION® esiRNA - EHU147041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19004 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19004 from Sigma-Aldrich
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SDHC siRNA (Human) - CRH4316 from Cohesion Biosciences
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SDHC RNAi - H00006391-R04 from Novus Biologicals
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SDHC - MBS8202947 from MyBioSource
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shRNA set against Human SDHC (NM_003001.3) - SHH403428 from Creative biogene
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shRNA set against Human SDHC(NM_001035513.1) - SHR192198 from Creative biogene
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shRNA set against Human SDHC(NM_003001.3) - SHR192234 from Creative biogene
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shRNA set against Human SDHC(NM_001035512.1) - SHR192252 from Creative biogene
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shRNA set against Human SDHC(NM_001035511.1) - SHR192324 from Creative biogene
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