Gene Symbol | SP110 |
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Entrez Gene | 3431 |
Alt Symbol | IFI41, IFI75, IPR1, VODI |
Species | Human |
Gene Type | protein-coding |
Description | SP110 nuclear body protein |
Other Description | interferon-induced protein 41, 30kD|interferon-induced protein 41/75|interferon-induced protein 75, 52kD|phosphoprotein 41|phosphoprotein 75|sp110 nuclear body protein|speckled 110 kDa|transcriptional coactivator Sp110 |
Swissprots | Q53TG2 Q14977 F5H1M1 Q9HCT8 Q14976 B4DVI4 Q9HB58 Q8WUZ6 |
Accessions | AAX93281 AAZ23281 AAZ23282 AAZ23283 AAZ23284 AAZ23285 AEK50372 AEK50373 AEK50374 EAW70915 EAW70916 EAW70917 EAW70918 EAW70919 Q9HB58 AF280094 AAF99318 AF280095 AAG09826 AK026488 AK128274 AK301097 BAG62696 AL579921 AL832300 BC012447 AAH12447 BC019059 AAH19059 BG231996 CA432211 DA958469 DB474530 JF432811 ADZ16028 L22343 AAD13402 XM_005246525 XP_005246582 XM_006712487 XP_006712550 XM_006712489 XP_006712552 XM_011511088 XP_011509390 XM_011511089 XP_011509391 XM_011511090 XP_011509392 XM_011511091 XP_011509393 XM_011511092 XP_011509394 NM_001185015 NP_001171944 NM_004509 NP_004500 NM_004510 NP_004501 NM_080424 NP_536349 |
Function | Transcription factor. May be a nuclear hormone receptor coactivator. Enhances transcription of genes with retinoic acid response elements (RARE). |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00185, ECO:0000255|PROSITE-ProRule:PRU00747, ECO:0000269|PubMed:10913195}. Note=Found in the nuclear body. |
Tissue Specificity | Highly expressed in peripheral blood leukocytes and spleen. Detected at intermediate levels in thymus, prostate, testis, ovary, small intestine and colon, and at low levels in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
Sp110 CRISPR/Cas9 KO Plasmid (h) - sc-405542 from Santa Cruz Biotechnology
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Sp110 HDR Plasmid (h) - sc-405542-HDR from Santa Cruz Biotechnology
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Sp110 Double Nickase Plasmid (h) - sc-405542-NIC from Santa Cruz Biotechnology
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Sp110 Double Nickase Plasmid (h2) - sc-405542-NIC-2 from Santa Cruz Biotechnology
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Sp110 CRISPR Activation Plasmid (h) - sc-405542-ACT from Santa Cruz Biotechnology
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Sp110 CRISPR Activation Plasmid (h2) - sc-405542-ACT-2 from Santa Cruz Biotechnology
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Sp110 Lentiviral Activation Particles (h) - sc-405542-LAC from Santa Cruz Biotechnology
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Sp110 Lentiviral Activation Particles (h2) - sc-405542-LAC-2 from Santa Cruz Biotechnology
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Sp110 siRNA (h) - sc-76542 from Santa Cruz Biotechnology
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Sp110 shRNA Plasmid (h) - sc-76542-SH from Santa Cruz Biotechnology
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Sp110 shRNA (h) Lentiviral Particles - sc-76542-V from Santa Cruz Biotechnology
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SP110 RNAi - H00003431-R01V from Novus Biologicals
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SP110 RNAi - H00003431-R03 from Novus Biologicals
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MISSION® esiRNA - EHU133111 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20365 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20365 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01513 from Sigma-Aldrich
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SP110 siRNA (Human) - CRH2324 from Cohesion Biosciences
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SP110 RNAi - H00003431-R01 from Novus Biologicals
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SP110 RNAi - H00003431-R02 from Novus Biologicals
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SP110 - MBS8210832 from MyBioSource
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Human SP110 siRNA - orb262826 from Biorbyt
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SP110 shRNA Plasmid (Human) - CHH2324 from Cohesion Biosciences
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SP110 miRNA 3'UTR clone - MiUTR3H-06818 from Creative biogene
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SP110 miRNA 3'UTR clone - MiUTR3H-06819 from Creative biogene
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