| Gene Symbol |
SLC35B2
|
| Entrez Gene |
347734
|
| Alt Symbol |
PAPST1, SLL, UGTrel4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
|
| Other Description |
3'-phosphoadenosine 5'-phosphosulfate transporter|PAPS transporter 1|adenosine 3'-phospho 5'-phosphosulfate transporter 1|putative MAPK-activating protein PM15|putative NF-kappa-B-activating protein 48|solute carrier family 35 member B2 variant 2|solute carrier family 35, member B2
|
| Swissprots |
B4DDM2 F5H7Y9 Q53GA3 Q8TB61 Q2VY06 Q96AR6 Q8NBK6 Q7Z2G3 B4DDU9 Q5T9W1 Q5T9W2
|
| Accessions |
EAX04261 Q8TB61 AB097021 BAC77374 AB097039 BAC77392 AB106538 BAC79117 AK075456 BAC11631 AK123749 BAG53951 AK223028 BAD96748 AK293251 BAG56783 AK293344 BAG56860 AK307572 AY491520 AAS79661 BC016839 AAH16839 BC024288 AAH24288 BI769501 CN370928 DA370522 DA383304 DA424392 DA817588 DB010939 DQ893314 ABM84240 DQ896628 ABM87627 DQ896632 ABM87631 EU176354 ABW03805 HY044970 NM_001286509 NP_001273438 NM_001286510 NP_001273439 NM_001286511 NP_001273440 NM_001286512 NP_001273441 NM_001286513 NP_001273442 NM_001286517 NP_001273446 NM_001286519 NP_001273448 NM_001286520 NP_001273449 NM_178148 NP_835361
|
| Function |
Mediates the transport of adenosine 3'-phospho 5'- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. May indirectly participate in activation of the NF- kappa-B and MAPK pathways. {ECO:0000269|PubMed:12716889}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000269|PubMed:12716889}; Multi-pass membrane protein {ECO:0000269|PubMed:12716889}.
|
| Tissue Specificity |
Highly expressed in the placenta, pancreas, mammary gland and skeletal muscle. Weakly or not expressed in colon, heart and prostate. {ECO:0000269|PubMed:12716889}.
|
