| Gene Symbol |
Hmgcs2
|
| Entrez Gene |
15360
|
| Alt Symbol |
1300002P16, mHS
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2
|
| Other Description |
3-hydroxy-3-methylglutaryl coenzyme A synthase|HMG-CoA synthase|hydroxymethylglutaryl-CoA synthase, mitochondrial
|
| Swissprots |
Q9DBM4 P54869 Q9DBK1 Q64740
|
| Accessions |
AAA92675 AAA92676 EDL38955 EDL38956 EDL38957 EDL38958 P54869 AK004865 BAB23626 AK004902 BAB23657 AK098104 BAC05233 BC014714 AAH14714 BC024744 AAH24744 NM_008256 NP_032282
|
| Function |
This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
|
| Subcellular Location |
Mitochondrion.
|
| Tissue Specificity |
Liver and kidney.
|
| Top Pathways |
Terpenoid backbone biosynthesis, PPAR signaling pathway, Synthesis and degradation of ketone bodies, Valine, leucine and isoleucine degradation, Butanoate metabolism
|