| Gene Symbol |
GRSF1
|
| Entrez Gene |
2926
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
G-rich RNA sequence binding factor 1
|
| Other Description |
G-rich sequence factor 1|GRSF-1
|
| Swissprots |
Q4W5S5 B3KPW0 Q8IWD6 Q8NBD2 Q6ZST3 Q12849
|
| Accessions |
AAY40942 EAX05631 EAX05632 EAX05633 EAX05634 Q12849 AI151431 AK023187 AK055499 BAG51526 AK056891 BAG51822 AK090755 BAC03513 AK094806 BAG52934 AK095799 BAG53131 AK097055 BAG53414 AK124124 BAG54012 AK124242 AK127161 BAC86863 AK294612 BAH11824 AK296287 BAH12303 AK298883 BAH12895 AV739732 BC040485 AAH40485 BC043201 DN990192 U07231 AAC95399 XM_005265681 XP_005265738 XM_011531897 XP_011530199 XM_011531898 XP_011530200 NM_001098477 NP_001091947 NM_002092 NP_002083
|
| Function |
Regulator of post-transcriptional mitochondrial gene expression, required for assembly of the mitochondrial ribosome and for recruitment of mRNA and lncRNA. Binds RNAs containing the 14 base G-rich element. Preferentially binds RNAs transcribed from three contiguous genes on the light strand of mtDNA, the ND6 mRNA, and the long non-coding RNAs for MT-CYB and MT-ND5, each of which contains multiple consensus binding sequences. {ECO:0000269|PubMed:23473033, ECO:0000269|PubMed:23473034}.
|
| Subcellular Location |
Cytoplasm. Mitochondrion matrix, mitochondrion nucleoid. Note=Forms granules that colocalize with foci of newly synthesized mtRNA next to mitochondrial nucleoids.
|