| Gene Symbol |
DDHD1
|
| Entrez Gene |
80821
|
| Alt Symbol |
PA-PLA1, PAPLA1, SPG28
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
DDHD domain containing 1
|
| Other Description |
DDHD domain-containing protein 1|phosphatidic acid-preferring phospholipase A1 homolog|phosphatidic acid-preferring phospholipase A1-like protein|phospholipase DDHD1|spastic paraplegia 28 (autosomal recessive)
|
| Swissprots |
Q9C0F8 Q8NEL9 Q8WVH3 Q96LL2 G5E9D1
|
| Accessions |
EAW80621 EAW80622 EAW80623 EAW80624 Q8NEL9 AB051492 BAB21796 AI871726 AK058137 BAB71679 AK091528 AK124546 AK125372 AK125556 AY173947 AAO49717 BC018014 AAH18014 BC030703 AAH30703 BY796571 DA212814 DQ315474 ABC43196 GU376468 ADB80245 XM_005268102 XP_005268159 XM_005268103 XP_005268160 XM_005268105 XP_005268162 XM_011537188 XP_011535490 XM_011537189 XP_011535491 NM_001160147 NP_001153619 NM_001160148 NP_001153620 NM_030637 NP_085140
|
| Function |
Phospholipase that hydrolyzes phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid. The different isoforms may change the substrate specificity. {ECO:0000269|PubMed:22922100}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:15623529}.
|
| Tissue Specificity |
Highly expressed in testis. Also expressed in brain, spleen and lung. Only expressed in cerebellum in fetal brain. {ECO:0000269|PubMed:9488669}.
|