Gene Symbol | CLRN1 |
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Entrez Gene | 7401 |
Alt Symbol | RP61, USH3, USH3A |
Species | Human |
Gene Type | protein-coding |
Description | clarin 1 |
Other Description | Usher syndrome type-3 protein|clarin-1 |
Swissprots | P58418 E1ACU9 Q8N6A9 D3DNJ3 |
Accessions | EAW78814 EAW78815 EAW78816 P58418 AF388366 AAL09581 AF388368 AAL09582 AF482697 AAN07148 AF495717 AAM88774 BC074970 AAH74970 BC074971 AAH74971 BM666773 HM626132 ADM63096 HM626133 ADM63097 HM626134 ADM63098 HM626135 ADM63099 HM626136 ADM63100 XR_924167 NM_001195794 NP_001182723 NM_001256819 NP_001243748 NM_052995 NP_443721 NM_174878 NP_777367 NR_046380 NM_174880 |
Function | May have a role in the excitatory ribbon synapse junctions between hair cells and cochlear ganglion cells and presumably also in analogous synapses within the retina. {ECO:0000269|PubMed:12080385}. |
Subcellular Location | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Widely expressed. Found in the retina. |
USH3A CRISPR/Cas9 KO Plasmid (h) - sc-406438 from Santa Cruz Biotechnology
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USH3A HDR Plasmid (h) - sc-406438-HDR from Santa Cruz Biotechnology
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USH3A Double Nickase Plasmid (h) - sc-406438-NIC from Santa Cruz Biotechnology
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USH3A Double Nickase Plasmid (h2) - sc-406438-NIC-2 from Santa Cruz Biotechnology
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USH3A CRISPR Activation Plasmid (h) - sc-406438-ACT from Santa Cruz Biotechnology
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USH3A CRISPR Activation Plasmid (h2) - sc-406438-ACT-2 from Santa Cruz Biotechnology
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USH3A Lentiviral Activation Particles (h) - sc-406438-LAC from Santa Cruz Biotechnology
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USH3A Lentiviral Activation Particles (h2) - sc-406438-LAC-2 from Santa Cruz Biotechnology
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USH3A siRNA (h) - sc-63191 from Santa Cruz Biotechnology
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USH3A shRNA Plasmid (h) - sc-63191-SH from Santa Cruz Biotechnology
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USH3A shRNA (h) Lentiviral Particles - sc-63191-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN6261 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6261 from Sigma-Aldrich
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CLRN1 siRNA (Human) - CRH5061 from Cohesion Biosciences
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CLRN1 - MBS8235579 from MyBioSource
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shRNA set against Human CLRN1 (NM_052995.2) - SHH265649 from Creative biogene
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shRNA set against Human CLRN1(NM_052995.2) - SHG184195 from Creative biogene
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shRNA set against Human CLRN1(NM_174878.2) - SHG184249 from Creative biogene
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CLRN1 shRNA Plasmid (Human) - CHH5061 from Cohesion Biosciences
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CLRN1 miRNA 3'UTR clone - MiUTR1H-02237 from Creative biogene
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CLRN1 miRNA 3'UTR clone - MiUTR1H-02238 from Creative biogene
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