Gene Symbol | CYP3A7 |
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Entrez Gene | 1551 |
Alt Symbol | CP37, CYPIIIA7, P-450(HFL33), P-450111A7, P450-HFLA |
Species | Human |
Gene Type | protein-coding |
Description | cytochrome P450, family 3, subfamily A, polypeptide 7 |
Other Description | aryl hydrocarbon hydroxylase|cytochrome P450 3A7|cytochrome P450, subfamily IIIA, polypeptide 7|cytochrome P450-HFLA|flavoprotein-linked monooxygenase|microsomal monooxygenase|xenobiotic monooxygenase |
Swissprots | P24462 Q9H241 A4D288 |
Accessions | AAG32289 EAL23867 EAW76637 P24462 BC067436 AAH67436 BC069780 BX643367 BX647143 D00408 BAA00310 NM_000765 NP_000756 |
Function | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. |
Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
Top Pathways | Steroid hormone biosynthesis, Chemical carcinogenesis, Retinol metabolism |
CYP3A7 CRISPR/Cas9 KO Plasmid (h) - sc-401319 from Santa Cruz Biotechnology
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CYP3A7 HDR Plasmid (h) - sc-401319-HDR from Santa Cruz Biotechnology
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CYP3A7 Double Nickase Plasmid (h) - sc-401319-NIC from Santa Cruz Biotechnology
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CYP3A7 Double Nickase Plasmid (h2) - sc-401319-NIC-2 from Santa Cruz Biotechnology
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CYP3A7 CRISPR Activation Plasmid (h) - sc-401319-ACT from Santa Cruz Biotechnology
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CYP3A7 CRISPR Activation Plasmid (h2) - sc-401319-ACT-2 from Santa Cruz Biotechnology
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CYP3A7 Lentiviral Activation Particles (h) - sc-401319-LAC from Santa Cruz Biotechnology
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CYP3A7 Lentiviral Activation Particles (h2) - sc-401319-LAC-2 from Santa Cruz Biotechnology
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CYP3A7 siRNA (h) - sc-44708 from Santa Cruz Biotechnology
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Cyp3A7 shRNA Plasmid (h) - sc-44708-SH from Santa Cruz Biotechnology
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Cyp3A7 shRNA (h) Lentiviral Particles - sc-44708-V from Santa Cruz Biotechnology
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CYP3A7 RNAi - H00001551-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN6888 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6888 from Sigma-Aldrich
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CYP3A7 siRNA (Human) - CRH1095 from Cohesion Biosciences
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CYP3A7 - MBS8238882 from MyBioSource
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shRNA set against Human CYP3A (NM_000765.3) - SHH273445 from Creative biogene
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Human CYP3A7 siRNA - orb261597 from Biorbyt
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CYP3A7 shRNA Plasmid (Human) - CHH1095 from Cohesion Biosciences
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CYP3A7 miRNA 3'UTR clone - MiUTR3H-07583 from Creative biogene
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