| Gene Symbol |
LRP12
|
| Entrez Gene |
29967
|
| Alt Symbol |
ST7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
low density lipoprotein receptor-related protein 12
|
| Other Description |
low-density lipoprotein receptor-related protein 12|suppressor of tumorigenicity 7 protein
|
| Swissprots |
A8K137 B4DRQ2 Q9Y561
|
| Accessions |
CAJ78400 EAW91895 EAW91896 EAW91897 EAW91898 Q9Y561 AB208957 BAD92194 AF064841 AF166350 AAD44360 AI828757 AK022991 AK126348 BAG54310 AK289752 BAF82441 AK299374 BAG61364 AL698796 BC017381 BC032109 AAH32109 CR749434 CAH18272 DC372924 DQ892323 ABM83249 DQ895525 ABM86451 NM_001135703 NP_001129175 NM_013437 NP_038465
|
| Function |
Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor. {ECO:0000269|PubMed:12809483}.
|
| Subcellular Location |
Membrane {ECO:0000269|PubMed:12809483}; Single-pass type I membrane protein {ECO:0000269|PubMed:12809483}. Membrane, coated pit {ECO:0000269|PubMed:12809483}.
|
| Tissue Specificity |
Widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas, but not in tissues consisting of a large number of epithelial cells, such as liver and kidney. Expressed at very low levels in a number of tumor-derived cell lines. {ECO:0000269|PubMed:9927190}.
|