Gene Symbol | TXNL4A |
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Entrez Gene | 10907 |
Alt Symbol | BMKS, DIB1, DIM1, SNRNP15, TXNL4, U5-15kD |
Species | Human |
Gene Type | protein-coding |
Description | thioredoxin-like 4A |
Other Description | DIM1 protein homolog|spliceosomal U5 snRNP-specific 15 kDa protein|thioredoxin-like 4|thioredoxin-like U5 snRNP protein U5-15kD|thioredoxin-like protein 4A |
Swissprots | P83876 B2RC18 |
Accessions | EAW66639 EAW66640 EAW66641 P83876 AA923682 AF023611 AAB81950 AF023612 AAB81951 AF146373 AAF17332 AK308703 AK309098 AK314901 BAG37415 AL522879 AV729855 AW796546 BC001046 AAH01046 BC019272 AAH19272 BE385528 BF972457 BM922767 BQ011103 BU553165 CX870603 JF432486 ADZ15703 NM_001303471 NP_001290400 NM_001305557 NP_001292486 NM_001305563 NP_001292492 NM_001305564 NP_001292493 NM_006701 NP_006692 NR_131175 NR_131176 NR_131177 |
Function | Essential role in pre-mRNA splicing as component of the U5 snRNP and U4/U6-U5 tri-snRNP complexes that are involved in spliceosome assembly. {ECO:0000269|PubMed:10610776}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:20858735}. |
Top Pathways | Spliceosome |
Dim1 CRISPR/Cas9 KO Plasmid (h) - sc-407150 from Santa Cruz Biotechnology
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Dim1 HDR Plasmid (h) - sc-407150-HDR from Santa Cruz Biotechnology
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Dim1 Double Nickase Plasmid (h) - sc-407150-NIC from Santa Cruz Biotechnology
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Dim1 Double Nickase Plasmid (h2) - sc-407150-NIC-2 from Santa Cruz Biotechnology
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Dim1 CRISPR Activation Plasmid (h) - sc-407150-ACT from Santa Cruz Biotechnology
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Dim1 CRISPR Activation Plasmid (h2) - sc-407150-ACT-2 from Santa Cruz Biotechnology
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Dim1 Lentiviral Activation Particles (h) - sc-407150-LAC from Santa Cruz Biotechnology
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Dim1 Lentiviral Activation Particles (h2) - sc-407150-LAC-2 from Santa Cruz Biotechnology
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Dim1 siRNA (h) - sc-77145 from Santa Cruz Biotechnology
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Dim1 shRNA Plasmid (h) - sc-77145-SH from Santa Cruz Biotechnology
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Dim1 shRNA (h) Lentiviral Particles - sc-77145-V from Santa Cruz Biotechnology
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TXNL4A RNAi - H00010907-R01 from Novus Biologicals
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MISSION® esiRNA - EHU082181 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22315 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22315 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06399 from Sigma-Aldrich
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TXNL4A siRNA (Human) - CRH7436 from Cohesion Biosciences
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TXNL4A - MBS8209583 from MyBioSource
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shRNA set against Human TXNL4A (NM_006701.2) - SHH438352 from Creative biogene
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TXNL4A shRNA Plasmid (Human) - CHH7436 from Cohesion Biosciences
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TXNL4A miRNA 3'UTR clone - MiUTR1H-10903 from Creative biogene
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