Gene Symbol | LCT |
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Entrez Gene | 3938 |
Alt Symbol | LAC, LPH, LPH1 |
Species | Human |
Gene Type | protein-coding |
Description | lactase |
Other Description | lactase-glycosylceramidase|lactase-phlorizin hydrolase|lactase-phlorizin hydrolase-1 |
Swissprots | Q4ZG58 P09848 |
Accessions | AAA59504 AAX88924 AAZ17378 EAX11622 P09848 BC156075 AAI56076 BC156950 AAI56951 X07994 CAA30801 NM_002299 NP_002290 |
Function | LPH splits lactose in the small intestine. |
Subcellular Location | Apical cell membrane; Single-pass type I membrane protein. Note=Brush border. |
Tissue Specificity | Intestine. |
Top Pathways | Carbohydrate digestion and absorption, Galactose metabolism |
LCT CRISPR/Cas9 KO Plasmid (h) - sc-406016 from Santa Cruz Biotechnology
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LCT HDR Plasmid (h) - sc-406016-HDR from Santa Cruz Biotechnology
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LCT Double Nickase Plasmid (h) - sc-406016-NIC from Santa Cruz Biotechnology
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LCT Double Nickase Plasmid (h2) - sc-406016-NIC-2 from Santa Cruz Biotechnology
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LCT CRISPR Activation Plasmid (h) - sc-406016-ACT from Santa Cruz Biotechnology
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LCT CRISPR Activation Plasmid (h2) - sc-406016-ACT-2 from Santa Cruz Biotechnology
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LCT Lentiviral Activation Particles (h) - sc-406016-LAC from Santa Cruz Biotechnology
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LCT Lentiviral Activation Particles (h2) - sc-406016-LAC-2 from Santa Cruz Biotechnology
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LCT siRNA (h) - sc-94992 from Santa Cruz Biotechnology
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LCT shRNA Plasmid (h) - sc-94992-SH from Santa Cruz Biotechnology
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LCT shRNA (h) Lentiviral Particles - sc-94992-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU049931 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11614 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11614 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR04137 from Sigma-Aldrich
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LCT siRNA (Human) - CRH2669 from Cohesion Biosciences
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Lactase RNAi - H00003938-R01 from Novus Biologicals
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shRNA set against Human LCT (NM_002299.2) - SHH329211 from Creative biogene
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shRNA set against Human LCT(NM_002299.2) - SHH144911 from Creative biogene
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Human LCT siRNA - orb263171 from Biorbyt
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LCT shRNA Plasmid (Human) - CHH2669 from Cohesion Biosciences
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LCT miRNA 3'UTR clone - MiUTR1H-05617 from Creative biogene
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