Gene Symbol |
IGLL1
|
Entrez Gene |
3543
|
Alt Symbol |
14.1, AGM2, CD179b, IGL1, IGL5, IGLJ14.1, IGLL, IGO, IGVPB, VPREB2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
immunoglobulin lambda-like polypeptide 1
|
Other Description |
CD179 antigen-like family member B|CD179b antigen|Pre-B lymphocyte-specific protein-2|ig lambda-5|immunoglobulin omega polypeptide chain|immunoglobulin-related 14.1 protein|immunoglobulin-related protein 14.1|lambda5
|
Swissprots |
P15814 Q0P681
|
Accessions |
AAA36096 CAA27229 CAA27231 EAW59583 EAW59584 P15814 BC012293 AAH12293 BC030239 AAH30239 DQ893578 ABM84504 DQ894640 ABM85566 M27749 AAA36100 XM_011530169 XP_011528471 NM_020070 NP_064455 NM_152855 NP_690594
|
Function |
Critical for B-cell development. {ECO:0000269|PubMed:9419212}.
|
Subcellular Location |
Secreted {ECO:0000269|PubMed:9419212}.
|
Tissue Specificity |
Expressed only in pre-B-cells and a special B- cell line (which is surface Ig negative). {ECO:0000269|PubMed:2128466}.
|
Top Pathways |
Primary immunodeficiency
|