Gene Symbol | IGLL1 |
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Entrez Gene | 3543 |
Alt Symbol | 14.1, AGM2, CD179b, IGL1, IGL5, IGLJ14.1, IGLL, IGO, IGVPB, VPREB2 |
Species | Human |
Gene Type | protein-coding |
Description | immunoglobulin lambda-like polypeptide 1 |
Other Description | CD179 antigen-like family member B|CD179b antigen|Pre-B lymphocyte-specific protein-2|ig lambda-5|immunoglobulin omega polypeptide chain|immunoglobulin-related 14.1 protein|immunoglobulin-related protein 14.1|lambda5 |
Swissprots | P15814 Q0P681 |
Accessions | AAA36096 CAA27229 CAA27231 EAW59583 EAW59584 P15814 BC012293 AAH12293 BC030239 AAH30239 DQ893578 ABM84504 DQ894640 ABM85566 M27749 AAA36100 XM_011530169 XP_011528471 NM_020070 NP_064455 NM_152855 NP_690594 |
Function | Critical for B-cell development. {ECO:0000269|PubMed:9419212}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:9419212}. |
Tissue Specificity | Expressed only in pre-B-cells and a special B- cell line (which is surface Ig negative). {ECO:0000269|PubMed:2128466}. |
Top Pathways | Primary immunodeficiency |
Lambda 5 CRISPR/Cas9 KO Plasmid (h) - sc-408742 from Santa Cruz Biotechnology
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Lambda 5 HDR Plasmid (h) - sc-408742-HDR from Santa Cruz Biotechnology
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Lambda 5 Double Nickase Plasmid (h) - sc-408742-NIC from Santa Cruz Biotechnology
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Lambda 5 Double Nickase Plasmid (h2) - sc-408742-NIC-2 from Santa Cruz Biotechnology
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Lambda 5 CRISPR Activation Plasmid (h) - sc-408742-ACT from Santa Cruz Biotechnology
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Lambda 5 CRISPR Activation Plasmid (h2) - sc-408742-ACT-2 from Santa Cruz Biotechnology
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Lambda 5 Lentiviral Activation Particles (h) - sc-408742-LAC from Santa Cruz Biotechnology
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Lambda 5 Lentiviral Activation Particles (h2) - sc-408742-LAC-2 from Santa Cruz Biotechnology
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Lambda 5 siRNA (h) - sc-44543 from Santa Cruz Biotechnology
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Lambda 5 shRNA Plasmid (h) - sc-44543-SH from Santa Cruz Biotechnology
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Lambda 5 shRNA (h) Lentiviral Particles - sc-44543-V from Santa Cruz Biotechnology
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Lambda5/IGLL1 RNAi - H00003543-R01 from Novus Biologicals
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Lambda5/IGLL1 RNAi - H00003543-R02 from Novus Biologicals
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MISSION® esiRNA - EHU148921 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10535 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10535 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03863 from Sigma-Aldrich
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IGLL1 siRNA (Human) - CRH2366 from Cohesion Biosciences
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IGLL1 - MBS8234938 from MyBioSource
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shRNA set against Human IGLL1 (NM_020070.3) - SHH317761 from Creative biogene
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Human IGLL1 siRNA - orb262868 from Biorbyt
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IGLL1 shRNA Plasmid (Human) - CHH2366 from Cohesion Biosciences
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IGLL1 miRNA 3'UTR clone - MiUTR3H-01159 from Creative biogene
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IGLL1 miRNA 3'UTR clone - MiUTR3H-01160 from Creative biogene
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