Gene Symbol | ADCY2 |
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Entrez Gene | 108 |
Alt Symbol | AC2, HBAC2 |
Species | Human |
Gene Type | protein-coding |
Description | adenylate cyclase 2 (brain) |
Other Description | 3',5'-cyclic AMP synthetase|ATP pyrophosphate-lyase 2|adenylate cyclase II|adenylate cyclase type 2|adenylate cyclase type II|adenylyl cyclase 2|type II adenylate cyclase |
Swissprots | Q9UPU2 Q9UDB2 Q08462 Q2NKL8 B7Z2C1 |
Accessions | CAI93390 EAX08097 Q08462 AB028983 BAA83012 AF070583 AAC28647 AF410885 AAP97285 AK123013 BAG53849 AK127036 AK294555 BAH11807 AK295531 BAG58443 AK299775 BAG61658 AK304041 BAG64952 AK307474 BC111743 AAI11744 BE677757 BK000372 DAA00058 CR749634 CAH18428 DB029098 DB481853 L21993 AAA64923 X74210 CAA52282 XM_011513942 XP_011512244 XR_427657 NM_020546 NP_065433 |
Function | This is a membrane-bound, calmodulin-insensitive adenylyl cyclase. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in brain. |
Top Pathways | Melanogenesis, Calcium signaling pathway, Thyroid hormone synthesis, cGMP-PKG signaling pathway, Oxytocin signaling pathway |
A cyclase II CRISPR/Cas9 KO Plasmid (h) - sc-402994 from Santa Cruz Biotechnology
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A cyclase II HDR Plasmid (h) - sc-402994-HDR from Santa Cruz Biotechnology
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A cyclase II Double Nickase Plasmid (h) - sc-402994-NIC from Santa Cruz Biotechnology
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A cyclase II Double Nickase Plasmid (h2) - sc-402994-NIC-2 from Santa Cruz Biotechnology
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A cyclase II CRISPR Activation Plasmid (h) - sc-402994-ACT from Santa Cruz Biotechnology
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A cyclase II CRISPR Activation Plasmid (h2) - sc-402994-ACT-2 from Santa Cruz Biotechnology
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A cyclase II Lentiviral Activation Particles (h) - sc-402994-LAC from Santa Cruz Biotechnology
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A cyclase II Lentiviral Activation Particles (h2) - sc-402994-LAC-2 from Santa Cruz Biotechnology
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A cyclase II siRNA (h) - sc-40317 from Santa Cruz Biotechnology
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A cyclase II shRNA Plasmid (h) - sc-40317-SH from Santa Cruz Biotechnology
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A cyclase II shRNA (h) Lentiviral Particles - sc-40317-V from Santa Cruz Biotechnology
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Adenylate Cyclase 2 RNAi - H00000108-R01 from Novus Biologicals
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MISSION® esiRNA - EHU078821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2861 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2861 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR13921 from Sigma-Aldrich
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ADCY2 siRNA (Human) - CRH0071 from Cohesion Biosciences
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ADCY2 - MBS8222308 from MyBioSource
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Human ADCY2 siRNA - orb260573 from Biorbyt
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ADCY2 shRNA Plasmid (Human) - CHH0071 from Cohesion Biosciences
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