Gene Symbol | CALM3 |
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Entrez Gene | 808 |
Alt Symbol | HEL-S-72, PHKD, PHKD3 |
Species | Human |
Gene Type | protein-coding |
Description | calmodulin 3 (phosphorylase kinase, delta) |
Other Description | caM|calmodulin|epididymis secretory protein Li 72|prepro-calmodulin 3 |
Swissprots | Q13942 P62158 Q96HK3 Q53S29 |
Accessions | CAA36839 CAE93898 EAW57425 EAW57426 EAW57427 EAW57428 EAW57429 AK094964 AK295927 BAG58713 AK310762 AL050207 AW883334 BC005137 AAH05137 BC006182 AAH06182 BG753029 BT006855 AAP35501 FJ224310 ACI46002 J04046 AAA51918 NM_005184 NP_005175 |
Function | Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. {ECO:0000269|PubMed:16760425, ECO:0000269|PubMed:23893133}. |
Subcellular Location | Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:16760425}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:16760425}. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules. |
Top Pathways | Estrogen signaling pathway, Rap1 signaling pathway, Alcoholism, cAMP signaling pathway, Circadian entrainment |
CaM III CRISPR/Cas9 KO Plasmid (h) - sc-400953 from Santa Cruz Biotechnology
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CaM III HDR Plasmid (h) - sc-400953-HDR from Santa Cruz Biotechnology
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CaM III Double Nickase Plasmid (h) - sc-400953-NIC from Santa Cruz Biotechnology
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CaM III Double Nickase Plasmid (h2) - sc-400953-NIC-2 from Santa Cruz Biotechnology
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CaM III CRISPR Activation Plasmid (h) - sc-400953-ACT from Santa Cruz Biotechnology
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CaM III CRISPR Activation Plasmid (h2) - sc-400953-ACT-2 from Santa Cruz Biotechnology
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CaM III Lentiviral Activation Particles (h) - sc-400953-LAC from Santa Cruz Biotechnology
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CaM III Lentiviral Activation Particles (h2) - sc-400953-LAC-2 from Santa Cruz Biotechnology
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CaM III siRNA (h) - sc-105178 from Santa Cruz Biotechnology
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CaM III shRNA Plasmid (h) - sc-105178-SH from Santa Cruz Biotechnology
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CaM III shRNA (h) Lentiviral Particles - sc-105178-V from Santa Cruz Biotechnology
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Calmodulin 3 RNAi - H00000808-R01 from Novus Biologicals
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MISSION® esiRNA - EHU143521 from Sigma-Aldrich
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MISSION® siRNA - SIHK0232 from Sigma-Aldrich
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MISSION® siRNA - SIHK0233 from Sigma-Aldrich
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MISSION® siRNA - SIHK0231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5302 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5302 from Sigma-Aldrich
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CALM3 siRNA (Human) - CRH0564 from Cohesion Biosciences
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CaM III CRISPR/Cas9 KO Plasmid (h2) - sc-400953-KO-2 from Santa Cruz Biotechnology
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CaM III HDR Plasmid (h2) - sc-400953-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CALM3 (NM_005184.2) - SHH253829 from Creative biogene
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shRNA set against Human CALM3(NM_005184.2) - SHG137373 from Creative biogene
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CALM3 shRNA Plasmid (Human) - CHH0564 from Cohesion Biosciences
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CALM3 miRNA 3'UTR clone - MiUTR1H-01626 from Creative biogene
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