Gene Symbol | CPA6 |
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Entrez Gene | 57094 |
Alt Symbol | CPAH, ETL5, FEB11 |
Species | Human |
Gene Type | protein-coding |
Description | carboxypeptidase A6 |
Other Description | carboxypeptidase B |
Swissprots | Q8N4T0 Q8NEX8 Q8TDE8 Q9NRI9 |
Accessions | AAM19307 EAW86937 EAW86938 EAW86939 Q8N4T0 AF221594 AAF91231 AY044833 AAK84941 BC033684 AAH33684 BI756197 BK000188 DAA00037 BP421438 DQ892043 ABM82969 DQ895237 ABM86163 XM_011517569 XP_011515871 XM_011517570 XP_011515872 NM_020361 NP_065094 NM_001127445 |
Function | May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. {ECO:0000269|PubMed:18178555}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:18178555}. |
Tissue Specificity | Expressed in the hippocampus, nucleus raphe, and cortex. {ECO:0000269|PubMed:21922598}. |
CPA6 CRISPR/Cas9 KO Plasmid (h) - sc-418503 from Santa Cruz Biotechnology
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CPA6 HDR Plasmid (h) - sc-418503-HDR from Santa Cruz Biotechnology
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CPA6 Double Nickase Plasmid (h) - sc-418503-NIC from Santa Cruz Biotechnology
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CPA6 Double Nickase Plasmid (h2) - sc-418503-NIC-2 from Santa Cruz Biotechnology
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CPA6 CRISPR Activation Plasmid (h) - sc-418503-ACT from Santa Cruz Biotechnology
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CPA6 CRISPR Activation Plasmid (h2) - sc-418503-ACT-2 from Santa Cruz Biotechnology
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CPA6 Lentiviral Activation Particles (h) - sc-418503-LAC from Santa Cruz Biotechnology
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CPA6 Lentiviral Activation Particles (h2) - sc-418503-LAC-2 from Santa Cruz Biotechnology
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CPA6 siRNA (h) - sc-77855 from Santa Cruz Biotechnology
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CPA6 shRNA Plasmid (h) - sc-77855-SH from Santa Cruz Biotechnology
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CPA6 shRNA (h) Lentiviral Particles - sc-77855-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU098521 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN2457 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2457 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02839 from Sigma-Aldrich
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CPA6 siRNA (Human) - CRJ1316 from Cohesion Biosciences
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CPA6 RNAi - H00057094-R01 from Novus Biologicals
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CPA6 - MBS8232871 from MyBioSource
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shRNA set against Human Cpa6 (NM_020361.4) - SHH268541 from Creative biogene
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CPA6 shRNA Plasmid (Human) - CHJ1316 from Cohesion Biosciences
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