Gene Symbol | IFNA21 |
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Entrez Gene | 3452 |
Alt Symbol | IFN-alphaI, LeIF F, leIF-F |
Species | Human |
Gene Type | protein-coding |
Description | interferon, alpha 21 |
Other Description | IFN-alpha-21|interferon alpha-21|interferon alpha-F|leukocyte interferon protein |
Swissprots | Q7M4Q4 Q5VWD1 Q14608 P01568 |
Accessions | EAW58623 P01568 BC069329 AAH69329 BC069372 AAH69372 BC069408 AAH69408 BC096699 AAH96699 BC101638 AAI01639 BC101640 AAI01641 M12350 AAA52718 M28586 AAA36041 V00540 CAA23801 X00145 CAA24980 NM_002175 NP_002166 |
Function | Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. {ECO:0000269|PubMed:1634550}. |
Subcellular Location | Secreted. |
Top Pathways | Cytosolic DNA-sensing pathway, Tuberculosis, Herpes simplex infection, Influenza A, PI3K-Akt signaling pathway |
IFN-α21 CRISPR/Cas9 KO Plasmid (h) - sc-418525 from Santa Cruz Biotechnology
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IFN-α21 HDR Plasmid (h) - sc-418525-HDR from Santa Cruz Biotechnology
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IFN-α21 Double Nickase Plasmid (h) - sc-418525-NIC from Santa Cruz Biotechnology
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IFN-α21 Double Nickase Plasmid (h2) - sc-418525-NIC-2 from Santa Cruz Biotechnology
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IFN-α21 CRISPR Activation Plasmid (h) - sc-418525-ACT from Santa Cruz Biotechnology
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IFN-α21 CRISPR Activation Plasmid (h2) - sc-418525-ACT-2 from Santa Cruz Biotechnology
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IFN-α21 Lentiviral Activation Particles (h) - sc-418525-LAC from Santa Cruz Biotechnology
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IFN-α21 Lentiviral Activation Particles (h2) - sc-418525-LAC-2 from Santa Cruz Biotechnology
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IFN-α21 siRNA (h) - sc-105558 from Santa Cruz Biotechnology
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IFN-α21 shRNA Plasmid (h) - sc-105558-SH from Santa Cruz Biotechnology
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IFN-α21 shRNA (h) Lentiviral Particles - sc-105558-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10483 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10483 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03910 from Sigma-Aldrich
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IFNA21 siRNA (Human) - CRH2340 from Cohesion Biosciences
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IFNA21 - MBS8233546 from MyBioSource
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shRNA set against Human IFNA21 (NM_002175.2) - SHH317077 from Creative biogene
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Human IFNA21 siRNA - orb262842 from Biorbyt
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IFNA21 shRNA Plasmid (Human) - CHH2340 from Cohesion Biosciences
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IFNA21 miRNA 3'UTR clone - MiUTR4H-TG11494 from Creative biogene
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