Gene Symbol |
ZNF16
|
Entrez Gene |
7564
|
Alt Symbol |
HZF1, KOX9
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
zinc finger protein 16
|
Other Description |
zinc finger protein KOX9|zinc finger protein Kruppel type 9
|
Swissprots |
D3DWP2 Q96FG0 P17020 Q9NRA4 B3KXM4 Q45SH7
|
Accessions |
CCQ43383 EAW82027 EAW82028 P17020 AF244088 AAF75235 AK096815 AK127625 BAG54536 AK226016 AL834451 CAD39111 BC010996 AAH10996 DQ117529 AAZ20773 X52340 CAA36566 XM_005272341 XP_005272398 XM_005272342 XP_005272399 XM_011517298 XP_011515600 NM_001029976 NP_001025147 NM_006958 NP_008889
|
Function |
Acts as a transcriptional activator. Promotes cell proliferation by facilitating the cell cycle phase transition from the S to G2/M phase. Involved in both the hemin- and phorbol myristate acetate (PMA)-induced erythroid and megakaryocytic differentiation, respectively. Plays also a role as an inhibitor of cell apoptosis. {ECO:0000269|PubMed:16628192, ECO:0000269|PubMed:19763908, ECO:0000269|PubMed:21874239}.
|
Subcellular Location |
Nucleus {ECO:0000269|PubMed:16628192}.
|
Tissue Specificity |
Ubiquitous. {ECO:0000269|PubMed:16628192}.
|