Gene Symbol | GSTT2 |
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Entrez Gene | 2953 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | glutathione S-transferase theta 2 (gene/pseudogene) |
Other Description | GST class-theta-2|glutathione S-transferase theta-2 |
Swissprots | P30712 P0CG29 Q9HD76 O60665 Q6IPV7 |
Accessions | AAC13317 AAG02373 EAW59625 EAW59626 P0CG29 AA682380 AK312043 BAG34980 BC002415 AAH02415 BC146929 AAI46930 BC146940 AAI46941 BC146943 AAI46944 BM804805 BM976631 BU584249 CD013993 CR456374 CAG30260 CR456500 CAG30386 CR456929 CAG33210 CU013079 CAK54510 CU013097 CAK54528 CU013367 CAK54809 CU013385 CAK54827 CX782167 DQ890742 ABM81668 HY221848 L38503 AAB63956 NM_000854 NP_000845 NM_001302670 NP_001289599 NR_126442 NR_126445 NR_126446 |
Function | Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Has a sulfatase activity. |
Subcellular Location | Cytoplasm. |
Tissue Specificity | Expressed at low levels in liver. In lung, expressed at low levels in ciliated bronchiolar cells, alveolar macrophages and alveolar type II cells. {ECO:0000269|PubMed:8761485}. |
Top Pathways | Chemical carcinogenesis, Glutathione metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450 |
GSTT2 CRISPR/Cas9 KO Plasmid (h) - sc-410806 from Santa Cruz Biotechnology
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GSTT2 HDR Plasmid (h) - sc-410806-HDR from Santa Cruz Biotechnology
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GSTT2 Double Nickase Plasmid (h) - sc-410806-NIC from Santa Cruz Biotechnology
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GSTT2 Double Nickase Plasmid (h2) - sc-410806-NIC-2 from Santa Cruz Biotechnology
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GSTT2 CRISPR Activation Plasmid (h) - sc-410806-ACT from Santa Cruz Biotechnology
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GSTT2 CRISPR Activation Plasmid (h2) - sc-410806-ACT-2 from Santa Cruz Biotechnology
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GSTT2 Lentiviral Activation Particles (h) - sc-410806-LAC from Santa Cruz Biotechnology
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GSTT2 Lentiviral Activation Particles (h2) - sc-410806-LAC-2 from Santa Cruz Biotechnology
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GSTT2 siRNA (h) - sc-105429 from Santa Cruz Biotechnology
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GSTT2 shRNA Plasmid (h) - sc-105429-SH from Santa Cruz Biotechnology
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GSTT2 shRNA (h) Lentiviral Particles - sc-105429-V from Santa Cruz Biotechnology
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GSTT2 RNAi - H00002953-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN9745 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9745 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03447 from Sigma-Aldrich
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GSTT2 siRNA (Human) - CRH1997 from Cohesion Biosciences
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GSTT2 - MBS8235407 from MyBioSource
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shRNA set against Human GSTT2 (NM_000854.3) - SHH308734 from Creative biogene
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shRNA set against Human GSTT2(NM_000854.3) - SHH108101 from Creative biogene
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GSTT2 shRNA Plasmid (Human) - CHH1997 from Cohesion Biosciences
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GSTT2 miRNA 3'UTR clone - MiUTR1H-04317 from Creative biogene
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