| Gene Symbol |
B4GALNT2
|
| Entrez Gene |
124872
|
| Alt Symbol |
B4GALT, GALGT2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
beta-1,4-N-acetyl-galactosaminyl transferase 2
|
| Other Description |
UDP-GalNAc:Neu5Aca2-3Galb-R b1,4-N-acetylgalactosaminyltransferase|UDP-GalNAc:Neu5Acalpha2-3Galbeta-R beta1,4-N-acetylgalactosaminyltransferase|beta 1,4 N-acetylgalactosaminyltransferase/betal,4 GalNAcT/Sda-GalNAcT|beta-1,4 N-acetylgalactosaminyltransferase 2|beta-4-N-acetylgalactosaminyltransferase|sd(a) beta-1,4-GalNAc transferase|sda beta-1,4-GalNAc transferase
|
| Swissprots |
B4DZE4 Q8NHY0 Q86Y40 Q14CP1
|
| Accessions |
EAW94690 EAW94691 Q8NHY0 AF510036 AAM34756 AJ517770 CAD57148 AJ517771 CAD57149 AK302876 BAG64056 BC113675 AAI13676 BC113677 AAI13678 HQ258321 ADR83075 HQ258467 ADR83221 S83275 AAN86706 XM_011524314 XP_011522616 NM_001159387 NP_001152859 NM_001159388 NP_001152860 NM_153446 NP_703147
|
| Function |
Involved in the synthesis of the Sd(a) antigen (Sia- alpha2,3-[GalNAc-beta1,4]Gal-beta1,4-GlcNAc), a carbohydrate determinant expressed on erythrocytes, the colonic mucosa and other tissues. Transfers a beta-1,4-linked GalNAc to the galactose residue of an alpha-2,3-sialylated chain. {ECO:0000269|PubMed:12678917, ECO:0000269|PubMed:14688233}.
|
| Subcellular Location |
Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Widely expressed. Highly expressed in colon and to a lesser extent in kidney, stomach, ileum and rectum. {ECO:0000269|PubMed:12678917}.
|