| Gene Symbol | Hsd17b4 |
|---|---|
| Entrez Gene | 15488 |
| Alt Symbol | 17-beta-HSD, 17[b]-HSD, 4, DBP, MFE-2, MFP2, MPF-2, Mfp-2, perMFE-2 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | hydroxysteroid (17-beta) dehydrogenase 4 |
| Other Description | 17-beta-HSD 4|17-beta-hydroxysteroid dehydrogenase 4|D-bifunctional protein|multifunctional protein 2|peroxisomal multifunctional enzyme type 2 |
| Swissprots | P51660 Q9DBM3 |
| Accessions | EDL09933 EDL09934 EDL09935 EDL09936 P51660 AK004866 BAB23627 AK088381 BAC40317 AK147182 BAE27744 AK152532 AK161655 BAE36514 AK166801 BAE39029 AK167060 BAE39222 AK169077 BAE40862 AK179910 AK180313 AK180864 AK185951 AK187517 AK199154 AK199910 AK205578 AK208618 AK214272 AK215381 AK215718 AK216937 AK218815 BC022175 AAH22175 X89998 CAA62015 NM_008292 NP_032318 |
| Function | Bifunctional enzyme acting on the peroxisomal beta- oxidation pathway for fatty acids. Catalyzes the formation of 3- ketoacyl-CoA intermediates from both straight-chain and 2-methyl- branched-chain fatty acids (By similarity). {ECO:0000250}. |
| Subcellular Location | Peroxisome {ECO:0000250}. |
| Tissue Specificity | Present in many tissues with highest concentrations in liver and kidney. |
| Top Pathways | Primary bile acid biosynthesis, Peroxisome |