Gene Symbol |
CST7
|
Entrez Gene |
8530
|
Alt Symbol |
CMAP
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
cystatin F (leukocystatin)
|
Other Description |
cystatin-7|cystatin-F|cystatin-like metastasis-associated protein|leukocystatin
|
Swissprots |
O76096 Q7Z4J8 Q6FH95 Q9UED4
|
Accessions |
BAB11886 CAD52872 EAX10116 O76096 AB015225 BAA34941 AF031824 AAC39788 AF036342 AAC35747 BC015507 AAH15507 BG547285 BT009825 AAP88827 CA449286 CR541860 CAG46658 CR541878 CAG46676 HQ448308 ADQ32788 NM_003650 NP_003641
|
Function |
Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system.
|
Subcellular Location |
Secreted {ECO:0000269|PubMed:12423348}. Cytoplasm {ECO:0000269|PubMed:12423348}.
|
Tissue Specificity |
Primarily expressed in peripheral blood cells and spleen.
|