Gene Symbol | MUC7 |
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Entrez Gene | 4589 |
Alt Symbol | MG2 |
Species | Human |
Gene Type | protein-coding |
Description | mucin 7, secreted |
Other Description | MUC-7|apo-MG2|mucin 7, salivary|mucin-7|salivary mucin-7 |
Swissprots | Q9UCD7 Q9UCD8 Q8TAX7 |
Accessions | EAX05621 Q8TAX7 AK093828 AK312855 BC025688 AAH25688 BX537739 BX647190 BX648903 BX648904 DB194707 DB199851 DB206328 DQ894077 ABM85003 L13283 NM_001145006 NP_001138478 NM_001145007 NP_001138479 NM_152291 NP_689504 |
Function | May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili. {ECO:0000269|PubMed:11378823, ECO:0000269|PubMed:8104046}. |
Subcellular Location | Secreted {ECO:0000269|PubMed:7690757}. |
Tissue Specificity | Expressed in salivary gland tissues and only in those that contain mucous acinar cells (e.g. sublingual and submandibular glands) and not in salivary glands containing only serous acinar cells (e.g. parotid gland). {ECO:0000269|PubMed:1445223, ECO:0000269|PubMed:7690757}. |
Top Pathways | Salivary secretion |
Mucin 7 CRISPR/Cas9 KO Plasmid (h) - sc-405487 from Santa Cruz Biotechnology
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Mucin 7 HDR Plasmid (h) - sc-405487-HDR from Santa Cruz Biotechnology
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Mucin 7 Double Nickase Plasmid (h) - sc-405487-NIC from Santa Cruz Biotechnology
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Mucin 7 Double Nickase Plasmid (h2) - sc-405487-NIC-2 from Santa Cruz Biotechnology
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Mucin 7 CRISPR Activation Plasmid (h) - sc-405487-ACT from Santa Cruz Biotechnology
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Mucin 7 CRISPR Activation Plasmid (h2) - sc-405487-ACT-2 from Santa Cruz Biotechnology
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Mucin 7 Lentiviral Activation Particles (h) - sc-405487-LAC from Santa Cruz Biotechnology
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Mucin 7 Lentiviral Activation Particles (h2) - sc-405487-LAC-2 from Santa Cruz Biotechnology
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Mucin 7 siRNA (h) - sc-43167 from Santa Cruz Biotechnology
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Mucin 7 shRNA Plasmid (h) - sc-43167-SH from Santa Cruz Biotechnology
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Mucin 7 shRNA (h) Lentiviral Particles - sc-43167-V from Santa Cruz Biotechnology
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MUC7 RNAi - H00004589-R01 from Novus Biologicals
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MISSION® esiRNA - EHU039201 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14762 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14762 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR08043 from Sigma-Aldrich
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MUC7 siRNA (Human) - CRH3023 from Cohesion Biosciences
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shRNA set against Human MUC7 (NM_152291.2) - SHH346992 from Creative biogene
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MUC7 shRNA Plasmid (Human) - CHH3023 from Cohesion Biosciences
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MUC7 miRNA 3'UTR clone - MiUTR3H-01448 from Creative biogene
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MUC7 miRNA 3'UTR clone - MiUTR3H-01449 from Creative biogene
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MUC7 miRNA 3'UTR clone - MiUTR3H-01450 from Creative biogene
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