Gene Symbol | PNKD |
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Entrez Gene | 25953 |
Alt Symbol | BRP17, DYT8, FKSG19, FPD1, KIPP1184, MR-1, MR1, PDC, PKND1, TAHCCP2 |
Species | Human |
Gene Type | protein-coding |
Description | paroxysmal nonkinesigenic dyskinesia |
Other Description | brain protein 17|myofibrillogenesis regulator 1|probable hydrolase PNKD|trans-activated by hepatitis C virus core protein 2 |
Swissprots | Q9NSX4 Q9BU26 Q8N490 Q9ULN6 Q96A48 Q9Y4T1 A8K1F2 |
Accessions | AAM73649 CCQ43513 EAW70602 EAW70603 EAW70604 EAW70605 EAW70606 Q8N490 AB033010 BAA86498 AF318057 AAL25716 AF417001 AAL08573 AF418285 AAL08580 AK289867 BAF82556 AK309308 AL080092 CAB45707 AL137675 CAB70870 AM393075 CAL37953 AM393168 CAL38046 AY039043 AAK83449 AY358680 AAQ89043 AY358753 AAQ89113 BC002937 AAH02937 BC007543 BC021118 AAH21118 BC036457 AAH36457 BI764334 BQ028777 BU553179 EU831585 ACE87185 EU831670 ACE86504 NM_001077399 NP_001070867 NM_015488 NP_056303 NM_022572 NP_072094 |
Function | Probable hydrolase that plays an aggravative role in the development of cardiac hypertrophy via activation of the NF-kappa- B signaling pathway. {ECO:0000250}. |
Subcellular Location | Isoform 3: Mitochondrion. |
Tissue Specificity | Isoform 1 is only expressed in the brain. Isoform 2 is ubiquitously detected with highest expression in skeletal muscle and detected in myocardial myofibrils. Variant Val-7 and Val-9 are detected in the brain only. {ECO:0000269|PubMed:15188056, ECO:0000269|PubMed:15262732, ECO:0000269|PubMed:15496428}. |
PNKD (D-14) - sc-161161 from Santa Cruz Biotechnology
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Anti-Probable hydrolase PNKD antibody - ab140115 from Abcam
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Anti-Probable hydrolase PNKD antibody - ab112936 from Abcam
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Anti-PNKD Antibody (aa42-70, AP) - LS-C266623 from LifeSpan Bioscience
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Anti-PNKD Antibody (aa42-70, APC) - LS-C266624 from LifeSpan Bioscience
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Anti-PNKD Antibody (aa42-70, Biotin) - LS-C266625 from LifeSpan Bioscience
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Anti-PNKD Antibody (aa42-70, Azide-free, HRP) - LS-C266627 from LifeSpan Bioscience
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Anti-PNKD Antibody (aa42-70, FITC) - LS-C266626 from LifeSpan Bioscience
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Anti-PNKD Antibody (aa42-70, PE) - LS-C266629 from LifeSpan Bioscience
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Anti-PNKD Antibody (aa41-70) - LS-C324131 from LifeSpan Bioscience
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Anti-PNKD Antibody (N-Terminus) - LS-C135170 from LifeSpan Bioscience
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Anti-PNKD Antibody (N-Terminus) - LS-C345436 from LifeSpan Bioscience
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Anti-PNKD Antibody (aa42-70) - LS-C163815 from LifeSpan Bioscience
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Anti-PNKD Antibody (aa164-342) - LS-C179064 from LifeSpan Bioscience
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PNKD Antibody - NBP1-88348 from Novus Biologicals
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PNKD Antibody - NBP1-74205 from Novus Biologicals
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PNKD Antibody - NBP1-88347 from Novus Biologicals
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PNKD Antibody - H00025953-B01P from Novus Biologicals
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Anti-MR-1 antibody produced in mouse - SAB1409084 from Sigma-Aldrich
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Anti-PNKD antibody produced in rabbit - HPA017068 from Sigma-Aldrich
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Anti-PNKD antibody produced in rabbit - HPA010134 from Sigma-Aldrich
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PNKD Antibody - N-terminal region (ARP44998_P050) - ARP44998_P050 from Aviva Systems Biology
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PNKD-Antibody-N-term - AP12567a from Abgent, a WuXi AppTec company
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PNKD Antibody - N-terminal region (OAAB08843) - OAAB08843 from Aviva Systems Biology
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PNKD antibody - orb78364 from Biorbyt
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