PNKD

Gene Symbol PNKD
Entrez Gene 25953
Alt Symbol BRP17, DYT8, FKSG19, FPD1, KIPP1184, MR-1, MR1, PDC, PKND1, TAHCCP2
Species Human
Gene Type protein-coding
Description paroxysmal nonkinesigenic dyskinesia
Other Description brain protein 17|myofibrillogenesis regulator 1|probable hydrolase PNKD|trans-activated by hepatitis C virus core protein 2
Swissprots Q9NSX4 Q9BU26 Q8N490 Q9ULN6 Q96A48 Q9Y4T1 A8K1F2
Accessions AAM73649 CCQ43513 EAW70602 EAW70603 EAW70604 EAW70605 EAW70606 Q8N490 AB033010 BAA86498 AF318057 AAL25716 AF417001 AAL08573 AF418285 AAL08580 AK289867 BAF82556 AK309308 AL080092 CAB45707 AL137675 CAB70870 AM393075 CAL37953 AM393168 CAL38046 AY039043 AAK83449 AY358680 AAQ89043 AY358753 AAQ89113 BC002937 AAH02937 BC007543 BC021118 AAH21118 BC036457 AAH36457 BI764334 BQ028777 BU553179 EU831585 ACE87185 EU831670 ACE86504 NM_001077399 NP_001070867 NM_015488 NP_056303 NM_022572 NP_072094
Function Probable hydrolase that plays an aggravative role in the development of cardiac hypertrophy via activation of the NF-kappa- B signaling pathway. {ECO:0000250}.
Subcellular Location Isoform 3: Mitochondrion.
Tissue Specificity Isoform 1 is only expressed in the brain. Isoform 2 is ubiquitously detected with highest expression in skeletal muscle and detected in myocardial myofibrils. Variant Val-7 and Val-9 are detected in the brain only. {ECO:0000269|PubMed:15188056, ECO:0000269|PubMed:15262732, ECO:0000269|PubMed:15496428}.

PNKD (D-14) - sc-161161 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PNKD (D-14): sc-161161. Western blot analysis of PNKD expression in mouse brain tissue extract.

Anti-Probable hydrolase PNKD antibody - ab140115 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Probable hydrolase PNKD antibody (ab140115) at 1/500 dilution + Human fetal liver lysate

Anti-Probable hydrolase PNKD antibody - ab112936 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Probable hydrolase PNKD antibody (ab112936) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

Anti-PNKD Antibody (aa42-70, AP) - LS-C266623 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PNKD Antibody (aa42-70, APC) - LS-C266624 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PNKD Antibody (aa42-70, Biotin) - LS-C266625 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PNKD Antibody (aa42-70, Azide-free, HRP) - LS-C266627 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PNKD Antibody (aa42-70, FITC) - LS-C266626 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PNKD Antibody (aa42-70, PE) - LS-C266629 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PNKD Antibody (aa41-70) - LS-C324131 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PNKD Antibody (N-Terminus) - LS-C135170 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PNKD antibody LS-C135170 Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.

Anti-PNKD Antibody (N-Terminus) - LS-C345436 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of PNKD Antibody with human HepG2 Whole Cell lysate.

Anti-PNKD Antibody (aa42-70) - LS-C163815 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PNKD Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-PNKD Antibody (aa164-342) - LS-C179064 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PNKD Antibody - NBP1-88348 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: PNKD Antibody [NBP1-88348] - Immunofluorescent staining of human cell line U-251 MG shows localization to mitochondria.

PNKD Antibody - NBP1-74205 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PNKD Antibody [NBP1-74205] - Mouse Heart lysate, concentration 1 ug/ml.

PNKD Antibody - NBP1-88347 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PNKD Antibody [NBP1-88347] - Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10Lane 2: Human cell line MCF-7

PNKD Antibody - H00025953-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: PNKD Antibody [H00025953-B01P] - Analysis of PNKD expression in human kidney.

Anti-MR-1 antibody produced in mouse - SAB1409084 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MR-1: <B>Cat. No. SAB1409084</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~42.4 kDa using PNKD transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PNKD antibody produced in rabbit - HPA017068 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PNKD: <B>Cat. No. HPA017068</B>: Immunohistochemical staining of human kidney shows cytoplasmic positivity in renal tubules.

Anti-PNKD antibody produced in rabbit - HPA010134 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PNKD: <B>Cat. No. HPA010134</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human cervix, uterine, tissue showing cytoplasmic positivity in squamous epithelial cells.

PNKD Antibody - N-terminal region (ARP44998_P050) - ARP44998_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PNKD-Antibody-N-term - AP12567a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
PNKD Antibody (N-term) (Cat. #AP12567a) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PNKD antibody detected the PNKD protein (arrow).

PNKD Antibody - N-terminal region (OAAB08843) - OAAB08843 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

PNKD antibody - orb78364 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of fetal liver lysate using PNKD antibody
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