Gene Symbol | HIGD2A |
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Entrez Gene | 192286 |
Alt Symbol | RCF1b |
Species | Human |
Gene Type | protein-coding |
Description | HIG1 hypoxia inducible domain family, member 2A |
Other Description | HIG1 domain family member 2A, mitochondrial|HIG1 domain family, member 2A|RCF1 homolog B |
Swissprots | Q9BW72 |
Accessions | EAW85081 EAW85082 Q9BW72 BC007502 AAH07502 DQ891893 ABM82819 DQ895080 ABM86006 NM_138820 NP_620175 |
Function | Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May be involved in cytochrome c oxidase activity. May play a role in the assembly of respiratory supercomplexes. {ECO:0000269|PubMed:22342701}. |
Subcellular Location | Mitochondrion membrane {ECO:0000255|PROSITE- ProRule:PRU00836, ECO:0000269|PubMed:22342701}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00836, ECO:0000269|PubMed:22342701}. Mitochondrion inner membrane {ECO:0000305|PubMed:22342701}. |
HIGD2A CRISPR/Cas9 KO Plasmid (h) - sc-406650 from Santa Cruz Biotechnology
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HIGD2A HDR Plasmid (h) - sc-406650-HDR from Santa Cruz Biotechnology
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HIGD2A Double Nickase Plasmid (h) - sc-406650-NIC from Santa Cruz Biotechnology
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HIGD2A Double Nickase Plasmid (h2) - sc-406650-NIC-2 from Santa Cruz Biotechnology
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HIGD2A CRISPR Activation Plasmid (h) - sc-406650-ACT from Santa Cruz Biotechnology
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HIGD2A CRISPR Activation Plasmid (h2) - sc-406650-ACT-2 from Santa Cruz Biotechnology
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HIGD2A Lentiviral Activation Particles (h) - sc-406650-LAC from Santa Cruz Biotechnology
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HIGD2A Lentiviral Activation Particles (h2) - sc-406650-LAC-2 from Santa Cruz Biotechnology
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HIGD2A siRNA (h) - sc-91606 from Santa Cruz Biotechnology
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HIGD2A shRNA Plasmid (h) - sc-91606-SH from Santa Cruz Biotechnology
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HIGD2A shRNA (h) Lentiviral Particles - sc-91606-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU131451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10036 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10036 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01624 from Sigma-Aldrich
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HIGD2A siRNA (Human) - CRJ6154 from Cohesion Biosciences
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HIGD2A - MBS8205651 from MyBioSource
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shRNA set against Human HIGD2A (NM_138820.2) - SHH312185 from Creative biogene
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shRNA set against Human HIGD2A(NM_138820.2) - SHH120827 from Creative biogene
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Human HIGD2A siRNA - orb276655 from Biorbyt
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HIGD2A shRNA Plasmid (Human) - CHJ6154 from Cohesion Biosciences
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HIGD2A miRNA 3'UTR clone - MiUTR1H-04503 from Creative biogene
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