| Gene Symbol | Nqo1 |
|---|---|
| Entrez Gene | 24314 |
| Alt Symbol | Dia4 |
| Species | Rat |
| Gene Type | protein-coding |
| Description | NAD(P)H dehydrogenase, quinone 1 |
| Other Description | DT-diaphorase|DTD|Diaphorase (NADH/NADPH)|NAD(P)H dehydrogenase [quinone] 1|NAD(P)H:menadione oxidoreductase|NAD(P)H:quinone oxidoreductase 1|QR1|azoreductase|menadione reductase|phylloquinone reductase|quinone reductase 1 |
| Swissprots | Q63478 P05982 |
| Accessions | AAA41989 AAA41990 EDL92478 P05982 BC083542 AAH83542 J02608 AAA41716 J02640 AAA41988 J02679 AAA41715 X17464 NM_017000 NP_058696 |
| Function | The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. {ECO:0000269|PubMed:1703398, ECO:0000269|PubMed:7862630}. |
| Subcellular Location | Cytoplasm {ECO:0000269|PubMed:1703398}. |
| Top Pathways | Ubiquinone and other terpenoid-quinone biosynthesis |