| Gene Symbol |
Nqo1
|
| Entrez Gene |
24314
|
| Alt Symbol |
Dia4
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
NAD(P)H dehydrogenase, quinone 1
|
| Other Description |
DT-diaphorase|DTD|Diaphorase (NADH/NADPH)|NAD(P)H dehydrogenase [quinone] 1|NAD(P)H:menadione oxidoreductase|NAD(P)H:quinone oxidoreductase 1|QR1|azoreductase|menadione reductase|phylloquinone reductase|quinone reductase 1
|
| Swissprots |
Q63478 P05982
|
| Accessions |
AAA41989 AAA41990 EDL92478 P05982 BC083542 AAH83542 J02608 AAA41716 J02640 AAA41988 J02679 AAA41715 X17464 NM_017000 NP_058696
|
| Function |
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. {ECO:0000269|PubMed:1703398, ECO:0000269|PubMed:7862630}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:1703398}.
|
| Top Pathways |
Ubiquinone and other terpenoid-quinone biosynthesis
|