BBS9

Gene Symbol BBS9
Entrez Gene 27241
Alt Symbol B1, C18, D1, PTHB1
Species Human
Gene Type protein-coding
Description Bardet-Biedl syndrome 9
Other Description PTH-responsive osteosarcoma B1 protein|bardet-Biedl syndrome 9 protein|parathyroid hormone-responsive B1 gene protein|protein PTHB1
Swissprots Q9Y699 Q7KYS7 E9PDC9 Q7KYS6 Q99844 Q3SYG4 Q9Y6A0 Q8N570 Q99854 P78514
Accessions AAB46606 EAL24466 EAL24467 EAW94015 EAW94016 EAW94017 EAW94018 Q3SYG4 AF095769 AF095770 AAD25980 AF095771 AAD25981 AK057660 BAG51948 AK091361 BAG52340 AK297436 BAG59863 AK314627 AL704922 BC032715 AAH32715 BC103831 AAI03832 BI254810 BX647385 U85994 AAB61918 U85995 AAB61919 U87408 AAB47568 XM_005249700 XP_005249757 XM_005249701 XP_005249758 XM_011515264 XP_011513566 XM_011515265 XP_011513567 XM_011515266 XP_011513568 XM_011515267 XP_011513569 XM_011515268 XP_011513570 XM_011515269 XP_011513571 XM_011515270 XP_011513572 NM_001033604 NP_001028776 NM_001033605 NP_001028777 NM_014451 NP_055266 NM_198428 NP_940820
Function The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization. {ECO:0000269|PubMed:17574030, ECO:0000269|PubMed:22072986}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium membrane. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite.
Tissue Specificity Widely expressed. Expressed in adult heart, skeletal muscle, lung, liver, kidney, placenta and brain, and in fetal kidney, lung, liver and brain. {ECO:0000269|PubMed:10221542, ECO:0000269|PubMed:16380913}.

BBS9 293 Cell Lysate - 407199 from ABBIOTEC

Category Cell Lysate
Prices $672.00
Sizes 100 µg

BBS9 Over-expression Lysate Product - GWB-DE2473 from Genway Biotech

Category Cell Lysate
Prices $756.00
Sizes 100 µg
Species Human

BBS9 Overexpression Lysate (Native) - NBP2-04684 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: BBS9 Overexpression Lysate (Adult Normal) [NBP2-04684] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for BBS9.

Panoply™ Human BBS9 Knockdown Stable Cell Line - CSC-DC001347 from Creative biogene

Category Cell Line
Species Human
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